Protein Alignment CG13796 and SLC6A13

DIOPT Version :10

• Sequence 1: NP_609140.2
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_057699.2
• Gene: SLC6A13 / 6540
• HGNCID: 11046
• Length: 602
• Species: Homo sapiens
• Alignment Length: 607
• Identity: 147/607 - (24%)
• Similarity: 249/607 - (41%)
• Gaps: 136/607 - (22%)

  Fly    73 TLERPYRHDKCRGRWAKSADFYFASCTHAFSSLIFSELSTFGIL---------HGGWLLFIIAYL 128
            |||        ||.|....:|..:         :..|:...|.:         :||. .|.|.||
Human    29 TLE--------RGHWNNKMEFVLS---------VAGEIIGLGNVWRFPYLCYKNGGG-AFFIPYL 75

  Fly   129 MGMLFYSLPIFLIQAFLGQFSSSGTISAFR-VAPIFKGIGYA----ILLLNLGTLTYYSIAAVVP 188
            :.:....:|:||::..|||::|.|.::|:| :.|||:|||||    ::|||:    ||.|.....
Human    76 VFLFTCGIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNV----YYIIVLAWA 136

  Fly   189 LIYTVNSIHPVIPWMSCNNSWNTQECSLHENYDVDDYRVDPHST---VEFFRSMIASTAKGSTSM 250
            |.|..:|....:||..|.:.|||:.|...:..:........::|   :||:...:...:.|...:
Human   137 LFYLFSSFTIDLPWGGCYHEWNTEHCMEFQKTNGSLNGTSENATSPVIEFWERRVLKISDGIQHL 201

  Fly   251 -SISWSMLIGVLSIWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVAVFLYL----LIHEQVT--- 307
             ::.|.:.:.:|..|::....:.|.|...|||:         :|.|.|.||    |:...||
Human   202 GALRWELALCLLLAWVICYFCIWKGVKSTGKVV---------YFTATFPYLMLVVLLIRGVTLPG 257

  Fly   308 ---------FDTLHYYWMPQ--LDSFDSILATARTALLMAGGALGPGWGSIITLSSYNNFRRDAE 361
                     :..|...|.||  :|:...|..:....|           |.:..|.|||.:..:..
Human   258 AAQGIQFYLYPNLTRLWDPQVWMDAGTQIFFSFAICL-----------GCLTALGSYNKYHNNCY 311

  Fly   362 RLSIWVC-LTHITIGLMGLLCCNVAHDHFEDHVGMM------PLHVDEKHHMQFLYLCFSYLFGR 419
            |..|.:| |...|..:.|....::        :|.|      |:....:......::.:......
Human   312 RDCIALCFLNSGTSFVAGFAIFSI--------LGFMSQEQGVPISEVAESGPGLAFIAYPRAVVM 368

  Fly   420 FTTTPNLWAFLFFGMIFLSELCALIIQMMSVITALFDEFETL---RSRRILVISSLVFCLTASSV 481
            ...:| |||..||.|:.|..|.:..:.:.|::|||.|.:..:   ::||.::|      |..|.|
Human   369 LPFSP-LWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPHVFRKKNRREVLI------LGVSVV 426

  Fly   482 YFCTQLGFSQLTQ--LPNLAVFTHLLISGILVLM--------TTWVYGRVRFQCDLQFMLGKTIS 536
            .|.  :|...||:  :....:|.:...||:.:|.        ..||||..||..:::.|:|....
Human   427 SFL--VGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAKRFYDNIEDMIGYRPW 489

  Fly   537 SFKIFFIRFATPIFLGLCLFQLTYLFTRDRIHDVLIYVSQ--------GLILLTAISYMV----- 588
            ....:...|.||   .:|  ..|:||:..: :..|.|..:        .|..|.|:|.||
Human   490 PLIKYCWLFLTP---AVC--TATFLFSLIK-YTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAW 548

  Fly   589 --YKVCRTNGDWRQRLQQCLAP 608
              |::....|.:|:|::|.:.|
Human   549 SLYRLGTLKGPFRERIRQLMCP 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_609140.2	SLC5-6-like_sbd	123..610	CDD:444915	136/548 (25%)
SLC6A13	NP_057699.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		SLC6sbd_GAT2	32..575	CDD:271396	144/596 (24%)