Protein Alignment CG13796 and SLC6A11

DIOPT Version :10

• Sequence 1: NP_609140.2
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_055044.1
• Gene: SLC6A11 / 6538
• HGNCID: 11044
• Length: 632
• Species: Homo sapiens
• Alignment Length: 651
• Identity: 156/651 - (23%)
• Similarity: 258/651 - (39%)
• Gaps: 153/651 - (23%)

  Fly    34 EPVETES-GGGMGGSLALAAR--RI-RSRQVHSMAVRTGSAYDTLERPYRHDKCRGRWAKSADFY 94
            |..|:|: |||.....|..||  |: |.:.||.                     ||.|....:|.
Human    17 EARESEAPGGGCSSGGAAPARHPRVKRDKAVHE---------------------RGHWNNKVEFV 60

  Fly    95 FASCTHAFSSLIFSELSTFGIL---------HGGWLLFIIAYLMGMLFYSLPIFLIQAFLGQFSS 150
            .:         :..|:...|.:         :||. .|:|.|::..:...:|:|.::..||||:|
Human    61 LS---------VAGEIIGLGNVWRFPYLCYKNGGG-AFLIPYVVFFICCGIPVFFLETALGQFTS 115

  Fly   151 SGTISAFR-VAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMSCNNSWNTQEC 214
            .|.|:.:| |.|:|:|||||..::......||.|.....:.|..|.....:||.:|.:.|||:.|
Human   116 EGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENC 180

  Fly   215 SLHENYDVDDY-------RVDPHSTVEFFRSMIASTAKGSTSM-SISWSMLIGVLSIWLVVLALL 271
            ...:..:|.:|       ...|  .:||:...:.:.:.|...: ::.|.:.:.:|:.|.:....:
Human   181 VEFQKLNVSNYSHVSLQNATSP--VMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCI 243

  Fly   272 LKPVAFIGKVLRCSCVLMFGFFVAVFLYLLIHEQVTF----DTLHYYWMPQLD--SFDSILATAR 330
            .|.....|||     |.:...|..:.|.:|:...||.    :.:.:|..|.|.  |...:...|.
Human   244 WKGTKSTGKV-----VYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAG 303

  Fly   331 TALLMAGGALGPGWGSIITLSSYNNFRRDAERLSIWVCLTH------------ITIGLM----GL 379
            |.:..:....   .|.:..|.||||:..:..|..|.:|..:            ..:|.|    |:
Human   304 TQIFFSYAIC---LGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGV 365

  Fly   380 LCCNVAHD-------HFEDHVGMMPLHVDEKHHMQFLYLCFSYLFGRFTTTPNLWAFLFFGMIFL 437
            ....||..       .:...|.||||                        :| |||.|||.|:..
Human   366 PIAEVAESGPGLAFIAYPKAVTMMPL------------------------SP-LWATLFFMMLIF 405

  Fly   438 SELCALIIQMMSVITALFDEF-ETLRS--RRILVISSLVFCLTASSV--YFCTQLGFSQLTQ--L 495
            ..|.:..:.:.|::||:.|.: :..|.  ||.|:|.:|       ||  ||   ||...||:  :
Human   406 LGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILAL-------SVISYF---LGLVMLTEGGM 460

  Fly   496 PNLAVFTHLLISGILVLMTT--------WVYGRVRFQCDLQFMLGKTISSFKIFFIRFATP-IFL 551
            ....:|.....||:.:|...        ||||..||..:::.|:|....|...:.....|| |..
Human   461 YIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICA 525

  Fly   552 GLCLFQLTYLFTRDRIHDVLIYVS--QGLILLTAISYMV-------YKVCRTNGDWRQRLQQCLA 607
            |:.:|.| ..:...:.:::..|.:  .|:..|.|:|.|:       ..|.:|.|...::||:...
Human   526 GIFIFFL-IKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQKLTT 589

  Fly   608 P 608
            |
Human   590 P 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_609140.2	SLC5-6-like_sbd	123..610	CDD:444915	135/549 (25%)
SLC6A11	NP_055044.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41		9/23 (39%)
		SLC6sbd_GAT3	49..590	CDD:212077	142/617 (23%)