Protein Alignment CG13796 and SLC6A8

DIOPT Version :10

• Sequence 1: NP_609140.2
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_005620.1
• Gene: SLC6A8 / 6535
• HGNCID: 11055
• Length: 635
• Species: Homo sapiens
• Alignment Length: 685
• Identity: 153/685 - (22%)
• Similarity: 260/685 - (37%)
• Gaps: 168/685 - (24%)

  Fly    21 SEHGTELPGDFI-----GEPVETESGGGM---GGSLALAARRIRSRQVH------SMAVRTGSAY 71
            |..|.|..|..|     |.|.:.:...|:   ||.||:..|...:||:.      ..||..|:.:
Human    12 SVSGDEKKGPLIAPGPDGAPAKGDGPVGLGTPGGRLAVPPRETWTRQMDFIMSCVGFAVGLGNVW 76

  Fly    72 DTLERPYRHDKCRGRWAKSADFYFASCTHAFSSLIFSELSTFGILHGGWLLFIIAYLMGMLFYSL 136
                                         .|..|.:.        :||. :|:|.|::..|...:
Human    77 -----------------------------RFPYLCYK--------NGGG-VFLIPYVLIALVGGI 103

  Fly   137 PIFLIQAFLGQFSSSGTISAFRVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIP 201
            |||.::..||||..:|:|:.:.:.|:|||:|||.:::.....|||.:.......|.|.|....:|
Human   104 PIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLP 168

  Fly   202 WMSCNNSWNTQEC---SLHE--------NYDVDDYRVDPHSTVEFFRSMIASTAKG-STSMSISW 254
            |.:|.::|||.:|   ..||        |...|.........:||:.:.:...:.| ....:::|
Human   169 WATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSGGLEVPGALNW 233

  Fly   255 SMLIGVLSIWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVAVFLY-----LLIHEQV---TFDTL 311
            .:.:.:|:.|::|...:.|.|...||::         :|.|.|.|     ||:...:   ..|.:
Human   234 EVTLCLLACWVLVYFCVWKGVKSTGKIV---------YFTATFPYVVLVVLLVRGVLLPGALDGI 289

  Fly   312 HYYWMPQLDSFDS--ILATARTALLMAGGALGPGWGSIITLSSYNNFRRDAERLSIWVCLTH--- 371
            .||..|......|  :...|.|.:..   :...|.|::..|.|||.|..:..:.:|.:.|.:
Human   290 IYYLKPDWSKLGSPQVWIDAGTQIFF---SYAIGLGALTALGSYNRFNNNCYKDAIILALINSGT 351

  Fly   372 ------ITIGLMGLLCCNVAHDHFEDHVGMMPLHVDE--KHHMQFLYLCFSYLFGRFTTTPNLWA 428
                  :...::|.:...            ..:|:.:  :......::.:..........| |||
Human   352 SFFAGFVVFSILGFMAAE------------QGVHISKVAESGPGLAFIAYPRAVTLMPVAP-LWA 403

  Fly   429 FLFFGMIFLSELCALIIQMMSVITALFD------EFETLRSRRILVISSLVFCLTASSVYFCTQL 487
            .|||.|:.|..|.:..:.:...||.|.|      .|...|...:.:..:|.|.:..|.|   |.
Human   404 ALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMV---TD- 464

  Fly   488 GFSQLTQLPNLAVFTHLLISGILVL--------MTTWVYGRVRFQCDLQFMLGKTISSFKIFFIR 544
            |...:.||     |.:...||..:|        :..||||..||..|:..|:|.....:..:...
Human   465 GGMYVFQL-----FDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWS 524

  Fly   545 FATP-IFLGLCLFQLTYLFTRDRIHDVLIYVS--------QGLILLTAISYMVYKVC-------- 592
            |.|| :.:|:.:|.:.|       ::.|:|.:        :.:....|:|.|   :|
Human   525 FFTPLVCMGIFIFNVVY-------YEPLVYNNTYVYPWWGEAMGWAFALSSM---LCVPLHLLGC 579

  Fly   593 --RTNGDWRQRLQQCLAP-----H-DWHPVDADNR 619
              |..|...:|.|....|     | ::...|||.|
Human   580 LLRAKGTMAERWQHLTQPIWGLHHLEYRAQDADVR 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_609140.2	SLC5-6-like_sbd	123..610	CDD:444915	127/558 (23%)
SLC6A8	NP_005620.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		5/15 (33%)
		SLC6sbd_CT1	52..621	CDD:271397	141/645 (22%)