Protein Alignment CG13796 and SLC6A7

DIOPT Version :10

• Sequence 1: NP_609140.2
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_016865256.1
• Gene: SLC6A7 / 6534
• HGNCID: 11054
• Length: 754
• Species: Homo sapiens
• Alignment Length: 621
• Identity: 153/621 - (24%)
• Similarity: 251/621 - (40%)
• Gaps: 118/621 - (19%)

  Fly    84 RGRWAKSADFYFASCTHAFSSLIFSELSTFGILHG--------------GWLLFIIAYLMGMLFY 134
            ||.|....||.               ||..|...|              |...|::.|.:.:...
Human   118 RGNWTGKLDFL---------------LSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAIC 167

  Fly   135 SLPIFLIQAFLGQFSSSGTISAFRVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPV 199
            .:|:|.::..||||||.|.::.::::|:|||.|.|:||:......||::.....|.|...|:...
Human   168 GIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSD 232

  Fly   200 IPWMSCNNSWNTQECSLHE-NYD---------------VDDYRVDPHSTV--EFFRSMIASTA-- 244
            :||..|.|.|||:.|..|. :.|               .::|....|:..  |..|..:.|.:
Human   233 LPWEHCGNWWNTELCLEHRVSKDGNGALPLNLTCTVSPSEEYWSQTHTEAEEEGRRGRVVSNSYP 297

  Fly   245 ----------------------KGSTSM----SISWSMLIGVLSIWLVVLALLLKPVAFIGKVLR 283
                                  :||..:    .|.|::.:.:|..|::|...:||.|...|||:
Human   298 QVIFLPQPPKAEEGVSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVV- 361

  Fly   284 CSCVLMFGFFVAVFLYL----LIHEQVT----FDTLHYYWMPQLDSFDSILATA--RTALLMAGG 338
                    :|.|.|.||    |:...||    :..:.:|..||   |..:|::.  ..|.|....
Human   362 --------YFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQ---FHHLLSSKVWIEAALQIFY 415

  Fly   339 ALGPGWGSIITLSSYNNFRRDAERLSIWVCLTH-ITIGLMGLLCCNVAHDHFEDHVGMMPLHVDE 402
            :||.|:|.::|.:|||.|.::..|.:..|.|.: ||..|.|....:|. .:....:| :|:....
Human   416 SLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVL-GYMSQELG-VPVDQVA 478

  Fly   403 KHHMQFLYLCFSYLFGRFTTTPNLWAFLFFGMIFLSELCALIIQMMSVITALFDEFE-TLRSRRI 466
            |......::.:.........:| .|:||||.|:....|.:....:.:::||:.|||. .||.::.
Human   479 KAGPGLAFVVYPQAMTMLPLSP-FWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKA 542

  Fly   467 LVISSLVFCLTASSVYFCTQLGFSQLTQLPNLAVFTHLLISGILV-LMTTWVYGRVRFQCDLQFM 530
            :....:...:....:...|..|...|..|.:.:....|::..|.. |..|.|||..||..|:..|
Human   543 VFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMM 607

  Fly   531 LG-KTISSFKIFFIRFATPIFLGLCLFQL---------TYLFTRDRIHDVLIYVSQGLILLTAI- 584
            || |....|:..::..:....|.|.::.:         :|.|..   ...|:.:..||:....|
Human   608 LGFKPGLYFRACWLFLSPATLLALMVYSIVKYQPSEYGSYRFPP---WAELLGILMGLLSCLMIP 669

  Fly   585 SYMVYKVCRTNGDWRQRLQQCLAP-HDWHPVDADNR 619
            :.|:..|.|..|...:||||...| .||.|...:||
Human   670 AGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENR 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_609140.2	SLC5-6-like_sbd	123..610	CDD:444915	138/557 (25%)
SLC6A7	XP_016865256.1	SLC6sbd_PROT	118..699	CDD:271390	150/613 (24%)