Protein Alignment CG13796 and SLC6A2

DIOPT Version :9

• Sequence 1: NP_001137807.1
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001165975.1
• Gene: SLC6A2 / 6530
• HGNCID: 11048
• Length: 628
• Species: Homo sapiens
• Alignment Length: 646
• Identity: 166/646 - (25%)
• Similarity: 276/646 - (42%)
• Gaps: 106/646 - (16%)

  Fly    36 VETESGGG-MGGSLALAARRIRSRQVHSMAVRTGSAYDTLERPYRHD-KCRGRWAKSADFYFASC 98
            |:.|:.|. .|....|.||    :....:.|:..:....|..|...| :.|..|.|..||..:..
Human    10 VQPENNGADTGPEQPLRAR----KTAELLVVKERNGVQCLLAPRDGDAQPRETWGKKIDFLLSVV 70

  Fly    99 THAFSSLIFSELSTFGIL---HGGWLLFIIAYLMGMLFYSLPIFLIQAFLGQFSSSGTISAFRVA 160
            ..|..   .:.:..|..|   :||. .|:|.|.:.::...:|:|.::..|||::..|..:.:::.
Human    71 GFAVD---LANVWRFPYLCYKNGGG-AFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKIC 131

  Fly   161 PIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMSCNNSWNTQECS---------- 215
            |.|||:|||::|:.|....||::.....|.|..:|....:||..|.::||:..|:
Human   132 PFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHTWNSPNCTDPKLLNGSVL 196

  Fly   216 -LHENYDVDDYRVDPHSTVEFFRSMIASTAKGSTSMSI---SWSMLIGVLSIWLVVLALLLKPVA 276
             .|..|  ..|:..|  ..||:...:....:.|....|   .|.:|:.::.:.:|:...|.|.|.
Human   197 GNHTKY--SKYKFTP--AAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVVIVLYFSLWKGVK 257

  Fly   277 FIGKVLRCSCVLMFGFFVAVFLYLLIHEQVTFD--------TLH--YYWMPQLDSFDSILATART 331
            ..|||:..:..|  .:||   |::|:...||..        .||  :|.:.:.    ::...|.|
Human   258 TSGKVVWITATL--PYFV---LFVLLVHGVTLPGASNGINAYLHIDFYRLKEA----TVWIDAAT 313

  Fly   332 ALLMAGGALGPGWGSIITLSSYNNF----RRDAERLSIWVCLTHITIG-----LMGLLCCNVAHD 387
            .:..   :||.|:|.:|..:|||.|    .|||...|...|:|....|     ::|.:    ||:
Human   314 QIFF---SLGAGFGVLIAFASYNKFDNNCYRDALLTSSINCITSFVSGFAIFSILGYM----AHE 371

  Fly   388 H---FED----HVGMMPLHVDEKHHMQFLYLCFSYLFGRFTTTPNLWAFLFFGMIFLSELCALII 445
            |   .||    ..|::.:...|         ..|.|.|     ...||.:||.|:....|.:.:.
Human   372 HKVNIEDVATEGAGLVFILYPE---------AISTLSG-----STFWAVVFFVMLLALGLDSSMG 422

  Fly   446 QMMSVITALFDEFETLRSRRILVISSLVFCLTASSVYFCTQLGFSQLTQLPNLAVFTHLLISGIL 510
            .|.:|||.|.|:|:.|:..|.|....:.|.....:::..|:.|...||.|...|..|.:|.:
Human   423 GMEAVITGLADDFQVLKRHRKLFTFGVTFSTFLLALFCITKGGIYVLTLLDTFAAGTSILFA--- 484

  Fly   511 VLM----TTWVYGRVRFQCDLQFMLGKTISSFKIFFIRFATPIFLGLCLFQLTYLFTRDRIHDVL 571
            |||    .:|.||..||..|:|.|:|.....:.....:|.:|.|| |.:..::.:..:...:|..
Human   485 VLMEAIGVSWFYGVDRFSNDIQQMMGFRPGLYWRLCWKFVSPAFL-LFVVVVSIINFKPLTYDDY 548

  Fly   572 IY------VSQGLILLTAI---SYMVYKVCRTNGDWRQRLQQCLAPHDWHPVDA--DNRRF 621
            |:      |..|:.|.:.:   .|::||...|.|...:||...:.|.:.|.:.|  |.|:|
Human   549 IFPPWANWVGWGIALSSMVLVPIYVIYKFLSTQGSLWERLAYGITPENEHHLVAQRDIRQF 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_001137807.1	SLC5-6-like_sbd	123..610	CDD:294310	140/539 (26%)
SLC6A2	NP_001165975.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		4/12 (33%)
		SLC6sbd_NET	56..612	CDD:212081	155/596 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820