DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13796 and slc6a16a

DIOPT Version :9

Sequence 1:	NP_001137807.1	Gene:	CG13796 / 34051	FlyBaseID:	FBgn0031939	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	XP_021327051.1	Gene:	slc6a16a / 555229	ZFINID:	ZDB-GENE-061009-43	Length:	693	Species:	Danio rerio

Alignment Length:	492	Identity:	117/492 - (23%)
Similarity:	189/492 - (38%)	Gaps:	107/492 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 GGWLLFIIAYLMGMLFYSLPIFLIQAFLGQFSSSGTISAFR-VAPIFKGIGYAILLLNLGTLTYY 181
            ||  .|::.|:|.:|...:|:|.::...||....|:|..:: ::|...||||:..::......||
Zfish    77 GG--AFMLLYVMLLLIIGVPLFFMELAAGQSIRQGSIGVWKHISPRLAGIGYSSCMVCFFVALYY 139

  Fly   182 SIAAVVPLIYTVNSIHPVIPWMSCNNSWNTQECSLHENYDVDDYRVDPHSTVEFFRSMIASTAKG 246
            ::.....|.|..||....:||..|       ...:..|..|.:......::..:||..:
Zfish   140 NVIIAWSLFYMGNSFQYPLPWEQC-------PVDMISNQTVKECAASSPTSYFWFRKAL------ 191

  Fly   247 STSMSISWS-----MLIG-VLSIWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVAVFLYLLIHEQ 305
            ..|.||..|     ::.| :|:.|.:|...::|.:....||:..|.|    |..||.:..||...
Zfish   192 DISDSIDQSGEFNPIMTGCLLAAWAIVCLAMIKGIKSSAKVMYFSSV----FPYAVLICFLIRGL 252

  Fly   306 V---TFDTLHYYWMPQLDSFDSILATARTALLMAGGALGPGWGSIITLSSY----NNFRRDAERL 363
            :   ..|.:.|.:.|:::.:..: ...|.|......|||.|:||:|..|||    ||..|||..:
Zfish   253 MLDGAIDGIKYMFYPKVEIWGEV-QVWRQAATQVFFALGLGYGSVIAYSSYNPIHNNCHRDAIMV 316

  Fly   364 SIWVCLTHITIGL-----MGLLCCNVAHDHFEDHVGMM--------------------PLHVDEK 403
            |....:|.:...|     :|....|:|.|....:|..|                    |..|..:
Zfish   317 SGINFMTSVLASLVVFVVLGFRAKNIALDCVATNVARMAEMAQTGSSQHWRPLFNMSDPKSVVLQ 381

  Fly   404 HHMQF------------------------------LYLCFSYLFGRFTTTPNLWAFLFFGMIFLS 438
            .:.|:                              .::.|:.....|..:| .|:.|||.|:...
Zfish   382 DYRQWYSSYGSLLGSNITDCDLEREMSKGVEGTGLAFIAFTEAMALFPASP-FWSTLFFLMLLNL 445

  Fly   439 ELCALIIQMMSVITALFDEFETL-RSRRILVISS--------LVFCLTASSVYFCTQLGFSQLTQ 494
            .|..:...|..::|.|.|.|..| |.:.:|.:.|        |:| ...|..||.|.......|
Zfish   446 GLSTMFGTMQGILTPLMDNFRVLGRHKTMLTVCSCILGFLIGLLF-TQRSGNYFVTMFDDYSAT- 508

  Fly   495 LPNLAVFTHLLISGILVLMTTWVYGRVRFQCDLQFML 531
            ||.:.|.....:|      ..|:||..||..|::.||
Zfish   509 LPLIIVVIFETVS------VAWIYGADRFLDDVEVML 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_001137807.1	SLC5-6-like_sbd	123..610	CDD:294310	115/487 (24%)
slc6a16a	XP_021327051.1	SLC6sbd-B0AT-like	42..617	CDD:271364	117/492 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910