Protein Alignment CG13796 and SLC6A20

DIOPT Version :10

• Sequence 1: NP_609140.2
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001372612.1
• Gene: SLC6A20 / 54716
• HGNCID: 30927
• Length: 603
• Species: Homo sapiens
• Alignment Length: 579
• Identity: 128/579 - (22%)
• Similarity: 228/579 - (39%)
• Gaps: 134/579 - (23%)

  Fly    81 DKCRGRWAKSADFYFASCTHAFSSLIFSELSTFGIL---HGGWLLFIIAYLMGMLFYSLPIFLIQ 142
            :|.|..||.|..|.||..::|..   ...:..|..|   :||. .|::.|::.::...:|:..::
Human     2 EKARPLWANSLQFVFACISYAVG---LGNVWRFPYLCQMYGGG-SFLVPYIIMLIVEGMPLLYLE 62

  Fly   143 AFLGQFSSSGTISAFR-VAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMSCN 206
            ..:||....|:|.|:| ::|...|:|.|.::::.....||::.......|..:|....:||..|.
Human    63 LAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVCP 127

  Fly   207 NSWNTQECSLHENYDVDDYRVDPHSTVEFF--RSMIASTAKGSTSMSISWSMLIGVLSIWLVVLA 269
            .:.|      |..||.:   .:..|:.::|  |..:..:.....:..:.|...:.:|..||||..
Human   128 LNGN------HTGYDEE---CEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLAWLVVYL 183

  Fly   270 LLLKPVAFIGKVLRCSCVLMFGFFVAVFLY-LLIHEQVTFDTLH-------YYWMPQLDSFDSIL 326
            .:|:.....|||:         :|.|...| :||...:...|||       |.:.|:..|..|:|
Human   184 CILRGTESTGKVV---------YFTASLPYCVLIIYLIRGLTLHGATNGLMYMFTPKGSSALSLL 239

  Fly   327 A-------------TARTALLMAGGALGPGWGSIITLSSYNNFRRDAERLSIWVCLTH------- 371
            |             .|.|.:..   :||.|:||:|..:|||....:.::.:|.|.|.:
Human   240 AFQIEQLANPKAWINAATQIFF---SLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFA 301

  Fly   372 --ITIGLMG---------------LLCCN--------VAHDHFEDHVGMMPLHVDEKHHMQFLYL 411
              :|..:.|               ||..|        :...:.|...|.:......|:...|..:
Human   302 SIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYSEMFPQI 366

  Fly   412 CFSYLFGRFTT--------------------TPNLWAFLFFGMIFLSELCALIIQMMSVITALFD 456
            ....|.....|                    ...||:.|:|.|:.:..:.:::....:::|.|.|
Human   367 KNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTD 431

  Fly   457 EFETLRSRRIL-------VISSLVFCLT--ASSVYFCTQLG------FSQLTQLPNLAVFTHLLI 506
            .       :|:       .||.|| ||.  |..:.|..:.|      |:...     |..:.|||
Human   432 S-------KIISSHLPKEAISGLV-CLVNCAIGMVFTMEAGNYWFDIFNDYA-----ATLSLLLI 483

  Fly   507 SGILVLMTTWVYGRVRFQCDLQFMLGKTISSF-KIFFIRFATPIFLGLCLFQLT-YLFT 563
            ..:..:...:|||..||:.||:.|.|:.:|.: |:.:...:..:.:.|.:|.|: |:.|
Human   484 VLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVSLFVFYLSDYILT 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_609140.2	SLC5-6-like_sbd	123..610	CDD:444915	115/534 (22%)
SLC6A20	NP_001372612.1	SLC6sbd_SIT1	2..588	CDD:271401	128/579 (22%)