Protein Alignment CG13796 and SLC6A18

DIOPT Version :9

• Sequence 1: NP_001137807.1
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_872438.2
• Gene: SLC6A18 / 348932
• HGNCID: 26441
• Length: 628
• Species: Homo sapiens
• Alignment Length: 648
• Identity: 148/648 - (22%)
• Similarity: 247/648 - (38%)
• Gaps: 151/648 - (23%)

  Fly    75 ERPYRHDKCRGRWAKSADFYFASCTHAFSSL----IFSEL-STFGILHGGWLLFIIAYLMGMLFY 134
            |||        :|...|. |..|||.....|    .|..| .|:|   ||  .|:|.|::.::|.
Human    17 ERP--------KWDNKAQ-YLLSCTGFAVGLGNIWRFPYLCQTYG---GG--AFLIPYVIALVFE 67

  Fly   135 SLPIFLIQAFLGQFSSSGTISAF-RVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHP 198
            .:|||.::..:||....|::..: .::|...|:|...:.|:.....||:......|.|.:||...
Human    68 GIPIFHVELAIGQRLRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVAWVLWYLLNSFQH 132

  Fly   199 VIPWMSC----NNSWNTQECSLHENYDVDDYRVDPHSTVEFF--RSMIASTAKGSTSMSISWSML 257
            .:||.||    |.:...:||             ...|.|.:|  |..:..||..:.|.||.|.:|
Human   133 PLPWSSCPPDLNRTGFVEEC-------------QGSSAVSYFWYRQTLNITADINDSGSIQWWLL 184

  Fly   258 IGVLSIWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVAVFLYLLIH----EQVTF----DTLHYY 314
            |.:.:.|.||...:::.:...|||:         :|.|:|.||::.    ..:|.    ..|.|.
Human   185 ICLAASWAVVYMCVIRGIETTGKVI---------YFTALFPYLVLTIFLIRGLTLPGATKGLIYL 240

  Fly   315 WMPQLDSFDS--ILATARTALLMAGGALGPGWGSIITLSSYNNFRRDAERLSIWVCLT------H 371
            :.|.:....:  :...|.|.:..   :|...:|..|..:|||:.|.|.::.::.:.|.      :
Human   241 FTPNMHILQNPRVWLDAATQIFF---SLSLAFGGHIAFASYNSPRNDCQKDAVVIALVNRMTSLY 302

  Fly   372 ITIGLMGLLCCNVAHDH--------------FE--------DHVGMMPLHVD---EKHHMQF-LY 410
            .:|.:..:|.....:|:              |:        |....:.:|::   .|...|. |.
Human   303 ASIAVFSVLGFKATNDYEHCLDRNILSLINDFDFPEQSISRDDYPAVLMHLNATWPKRVAQLPLK 367

  Fly   411 LCF------------SYLFGRFTTT----PN--LWAFLFFGMIFLSELCALIIQMMSVITALFD- 456
            .|.            ...|..||.|    |.  :||.|||||:|...|..:...:.:|||.|.|
Human   368 ACLLEDFLDKSASGPGLAFVVFTETDLHMPGAPVWAMLFFGMLFTLGLSTMFGTVEAVITPLLDV 432

  Fly   457 -------EFETLRSRRILVISSLVFCLTASSVYFCTQLGFSQLTQLPNLAVFTHLLISGILVLMT 514
                   ..|.|.....||......|.|..|..:..:: |......|||.:...|.:.|::
Human   433 GVLPRWVPKEALTGLVCLVCFLSATCFTLQSGNYWLEI-FDNFAASPNLLMLAFLEVVGVV---- 492

  Fly   515 TWVYGRVRFQCDLQFMLGKTISSFKIFFIRFATPIFLGLCLFQLTYLF----------------- 562
             :|||..||..|:.:|.|:..|.:.....|..:|:.|.:.:..:..||
Human   493 -YVYGMKRFCDDIAWMTGRRPSPYWRLTWRVVSPLLLTIFVAYIILLFWKPLRYKAWNPKYELFP 556

  Fly   563 -TRDRIHD-----VLIYVSQGLILLTAISYMVYKVCRTNGDWRQRLQQCLAPHDWHPVDADNR 619
             .:::::.     ..:.:|...:|...::.:...:.|....||.|  ......|..| |.|.|
Human   557 SRQEKLYPGWARAACVLLSLLPVLWVPVAALAQLLTRRRRTWRDR--DARPDTDMRP-DTDTR 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_001137807.1	SLC5-6-like_sbd	123..610	CDD:294310	127/584 (22%)
SLC6A18	NP_872438.2	SLC6sbd_B0AT3	17..591	CDD:212086	139/618 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	602..628		5/16 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810