DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13796 and CG10804

DIOPT Version :9

Sequence 1:	NP_001137807.1	Gene:	CG13796 / 34051	FlyBaseID:	FBgn0031939	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	NP_001138150.1	Gene:	CG10804 / 31317	FlyBaseID:	FBgn0029663	Length:	726	Species:	Drosophila melanogaster

Alignment Length:	611	Identity:	134/611 - (21%)
Similarity:	241/611 - (39%)	Gaps:	105/611 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 EQLNNCMLLGDCENSEHGTE-------------------LPGDFIGEPVETESGGGMGGSLALAA 52
            :||....|.|...:.|||..                   ...|...|..|.|......||.|..:
  Fly    25 DQLELRELRGRLVSKEHGVSHHHHTSLHHQPLYGATNQGFMSDAFDESSELEQDPPPFGSEASTS 89

  Fly    53 RRIRSRQVHSMAVRTGSA--YDTLERPYRHDKCRGRWAKSADFYFASCTHAFSSLIFSELSTFGI 115
            :    .:...:|:.|.||  .|.:|.....:: |..|.....|..|:..:|..   ...:..|..
  Fly    90 K----AKAELVAIATASADQQDIVEGEKEGEE-RESWDSKIMFLLATIGYAVG---LGNVWRFPY 146

  Fly   116 L---HGGWLLFIIAYLMGMLFYSLPIFLIQAFLGQFSSSGTISAF-RVAPIFKGIGYAILLLNLG 176
            |   :||. .|::.|.:.:....:|||.::..:||....|.|..: :|:|...|||.:..:::..
  Fly   147 LAQKNGGG-AFLVPYFIMLCIQGIPIFYLELAIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYI 210

  Fly   177 TLTYYSIAAVVPLIYTVNSIHPVIPWMSCNNSWNTQECSLHENYDVDDYRVDPH----STVEF-- 235
            ...||:......|||.::|....:||..|       ...|::|:..|.   :|.    |..:|
  Fly   211 VALYYNTIIAWCLIYLLHSFESPLPWADC-------PTRLYKNFTYDH---EPECVASSPTQFYW 265

  Fly   236 FRSMIASTAKGSTSMSISWSMLIGVLSIWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVAVFLYL 300
            :|:.:..:.......:.::.|.|.::..|.:|...:::.:...||:     |.|...|..|.|.:
  Fly   266 YRTTLQCSESVDMPENFNYHMAIALIVSWFLVYICMVQGITSSGKI-----VYMTAIFPYVVLII 325

  Fly   301 LIHEQVTF----DTLHYYWMPQLDS-FDSIL-ATARTALLMAGGALGPGWGSIITLSSY----NN 355
            .....:|.    |.:.:.:.|:.:: .|.:: ..|.|.:..   :||..:|.:|..|||    ||
  Fly   326 FFFRGITLKGAADGVAHLFTPRWETLLDPVVWLEAGTQIFF---SLGLAFGGLIAFSSYNPANNN 387

  Fly   356 FRRDAERLSIWVCLTHITIGLM---------------------GLLCCNVAHDHFEDHVGMMPLH 399
            ..|||..:|:..|.|.:..|::                     ||:..|..|     ::.:..|.
  Fly   388 CYRDAILVSLTNCGTSMFAGVVVFSVIGFKATATFDRCTEERNGLVAQNKTH-----NLPVCDLQ 447

  Fly   400 VDEKHHMQ---FLYLCFSYLFGRFTTTPNLWAFLFFGMIFLSELCALIIQMMSVITALFDE--FE 459
            .:..:...   ..::.|:....:|... .|||.|||.|:|...:.:....:..|:|:|.|.  |.
  Fly   448 TELANSASGTGLAFIIFTEAINQFPGA-QLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVDMKLFP 511

  Fly   460 TLRSRRILVISSLVFCLTASSVYFCTQLGFSQLTQLPN--LAVFTHLLISGILVLMTTWVYGRVR 522
            .|...  .::.:|.|.....|:.|....| |.:.||.:  ...|..|:|:....|..:::||..|
  Fly   512 NLPKE--YIVGALCFSCCTISMCFANGAG-SYIFQLMDSFAGNFPLLIIALFECLSISYIYGVRR 573

  Fly   523 FQCDLQFMLGKTISSFKIFFIRFATP 548
            |..|::.|.|...:.:.:|..::.:|
  Fly   574 FSDDIEMMTGSRPNFYWMFCWKYLSP 599

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_001137807.1	SLC5-6-like_sbd	123..610	CDD:294310	105/471 (22%)
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	113/511 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910