DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13796 and Slc6a7

DIOPT Version :9

Sequence 1:	NP_001137807.1	Gene:	CG13796 / 34051	FlyBaseID:	FBgn0031939	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	XP_006525992.1	Gene:	Slc6a7 / 240332	MGIID:	2147363	Length:	684	Species:	Mus musculus

Alignment Length:	581	Identity:	152/581 - (26%)
Similarity:	247/581 - (42%)	Gaps:	75/581 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 RGRWAKSADFYFASCTHAFSSLIFSELSTFGILHG--------------GWLLFIIAYLMGMLFY 134
            ||.|....||.               ||..|...|              |...|::.|.:.:...
Mouse    84 RGNWTGKLDFL---------------LSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAIC 133

  Fly   135 SLPIFLIQAFLGQFSSSGTISAFRVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPV 199
            .:|:|.::..||||||.|.::.::::|:|||.|.|:||:......||::.....|.|...|:...
Mouse   134 GIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSN 198

  Fly   200 IPWMSCNNSWNTQECSLHENYDVDD--YRVDPHSTV---EFFRSMIASTAKGSTSM----SISWS 255
            :||..|.|.|||:.|..|......:  ..::..|||   |.:.|......:||..:    .|.|:
Mouse   199 LPWEHCGNWWNTELCLEHRGPKSGNGVLPLNLSSTVSPSEEYWSRYVLHIQGSQGIGRPGEIRWN 263

  Fly   256 MLIGVLSIWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVAVFLYL----LIHEQVT----FDTLH 312
            :.:.:|..|::|...:||.|...|||:         :|.|.|.||    |:...||    :..:.
Mouse   264 LCLCLLLAWVIVFLCILKGVKSSGKVV---------YFTATFPYLILLMLLVRGVTLPGAWKGIQ 319

  Fly   313 YYWMPQLDSFDSILATA--RTALLMAGGALGPGWGSIITLSSYNNFRRDAERLSIWVCLTH-ITI 374
            :|..||   |..:|::.  ..|.|....:||.|:|.::|.:|||.|.::..|.:..|.|.: ||.
Mouse   320 FYLTPQ---FHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITS 381

  Fly   375 GLMGLLCCNVAHDHFEDHVGMMPLHVDEKHHMQFLYLCFSYLFGRFTTTPNLWAFLFFGMIFLSE 439
            .|.|....:|. .:....:| :|:....|......::.:.........:| .|:||||.|:....
Mouse   382 ILAGFAIFSVL-GYMSQELG-VPVDQVAKAGPGLAFVVYPQAMTMLPLSP-FWSFLFFFMLLTLG 443

  Fly   440 LCALIIQMMSVITALFDEFE-TLRSRRILVISSLVFCLTASSVYFCTQLGFSQLTQLPNLAVFTH 503
            |.:....:.:::||:.|||. .||.::.:....:...:....:...|..|...|..|.:.:....
Mouse   444 LDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFG 508

  Fly   504 LLISGILV-LMTTWVYGRVRFQCDLQFMLG-KTISSFKIFFIRFATPIFLGLCLFQLT------Y 560
            |::..|.. |..|.|||..||..|:..||| |....|:..::..:....|.|.::.:.      |
Mouse   509 LMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEY 573

  Fly   561 LFTRDRIHDVLIYVSQGLILLTAI-SYMVYKVCRTNGDWRQRLQQCLAP-HDWHPVDADNR 619
            ...|......|:.:..||:....| :.|:..|.|..|...:||||...| .||.|...:||
Mouse   574 GSYRFPAWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENR 634

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_001137807.1	SLC5-6-like_sbd	123..610	CDD:294310	137/517 (26%)
Slc6a7	XP_006525992.1	SLC5-6-like_sbd	84..628	CDD:382020	149/573 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820