DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13796 and Slc6a13

DIOPT Version :9

Sequence 1:	NP_001137807.1	Gene:	CG13796 / 34051	FlyBaseID:	FBgn0031939	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	XP_006237280.2	Gene:	Slc6a13 / 171163	RGDID:	620788	Length:	608	Species:	Rattus norvegicus

Alignment Length:	616	Identity:	145/616 - (23%)
Similarity:	252/616 - (40%)	Gaps:	148/616 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 TLERPYRHDKCRGRWAKSADFYFASCTHAFSSLIFSELSTFGIL---------HGGWLLFIIAYL 128
            ||||.        :|....:|..:         :..|:...|.:         :||. .|.|.||
  Rat    29 TLERE--------QWTNKMEFVLS---------VAGEIIGLGNVWRFPYLCYKNGGG-AFFIPYL 75

  Fly   129 MGMLFYSLPIFLIQAFLGQFSSSGTISAFR-VAPIFK------GIGYA----ILLLNLGTLTYYS 182
            :.:....:|:|.::..|||:::.|.|:|:| :.|||:      |||||    :.|||:    ||.
  Rat    76 IFLFTCGIPVFFLETALGQYTNQGGITAWRKICPIFEASVPSPGIGYASQMIVSLLNV----YYI 136

  Fly   183 IAAVVPLIYTVNSIHPVIPWMSCNNSWNTQEC----SLHENYDV-DDYRVDPHSTVEFFRSMIAS 242
            :.....|.|..:|....:||.||::.|||:.|    ..:.:.:| .:....|  .:||:...:..
  Rat   137 VVLAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKTNNSLNVTSENATSP--VIEFWERRVLK 199

  Fly   243 TAKGSTSM-SISWSMLIGVLSIWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVAVFLYL----LI 302
            .:.|...: |:.|.:::.:|..|::....:.|.|...|||:         :|.|.|.||    |:
  Rat   200 ISDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVV---------YFTATFPYLMLVVLL 255

  Fly   303 HEQVTF----DTLHYY--------WMPQ--LDSFDSILATARTALLMAGGALGPGWGSIITLSSY 353
            ...||.    ..:.:|        |.||  :|:...|..:....|           |.:..|.||
  Rat   256 IRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICL-----------GCLTALGSY 309

  Fly   354 NNFRRDAERLSIWVC-LTHITIGLMGLLCCNVAHDHFEDHVGMM------PLHVDEKHHMQFLYL 411
            |.:..:..|..:.:| |...|..:.|....::        :|.|      |:....:......::
  Rat   310 NKYHNNCYRDCVALCILNSSTSFVAGFAIFSI--------LGFMSQEQGVPISEVAESGPGLAFI 366

  Fly   412 CFSYLFGRFTTTPNLWAFLFFGMIFLSELCALIIQMMSVITALFDEFETL---RSRR---ILVIS 470
            .:.........:| |||..||.|:.|..|.:..:.:.|::|||.|.:..:   ::||   ||::|
  Rat   367 AYPRAVVMLPFSP-LWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREILILIVS 430

  Fly   471 SLVFCLTASSVYFCTQLGFSQLTQ--LPNLAVFTHLLISGILVLM--------TTWVYGRVRFQC 525
            .:.|.           :|...||:  :....:|.:...||:.:|.        ..||||..||..
  Rat   431 VVSFF-----------IGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGASRFYD 484

  Fly   526 DLQFMLG-KTISSFKIFFIRFATPIFLGLCLFQL------------TYLFTRDRIHDVLIYVSQG 577
            :::.|:| |.....|..::.|...:.|...||.|            ||.:..|.:..:|...|
  Rat   485 NIEDMIGYKPWPLIKYCWLFFTPAVCLATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSS-- 547

  Fly   578 LILLTAISYMVYKVCRTNGDWRQRLQQCLAP 608
            ::.:.|  :.:||:....|..|:||:|.:.|
  Rat   548 MVCIPA--WSIYKLRTLKGPLRERLRQLVCP 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_001137807.1	SLC5-6-like_sbd	123..610	CDD:294310	135/557 (24%)
Slc6a13	XP_006237280.2	SLC5-6-like_sbd	32..581	CDD:382020	142/613 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920