Protein Alignment CG13796 and Slc6a3

DIOPT Version :10

• Sequence 1: NP_609140.2
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_034150.1
• Gene: Slc6a3 / 13162
• MGIID: 94862
• Length: 619
• Species: Mus musculus
• Alignment Length: 607
• Identity: 148/607 - (24%)
• Similarity: 243/607 - (40%)
• Gaps: 124/607 - (20%)

  Fly    84 RGRWAKSADFYFASCTHA--------FSSLIFSELSTFGILHGGWLLFIIAYLMGMLFYSLPIFL 140
            |..|:|..||..:....|        |..|.:.        :||. .|::.||:.|:...:|:|.
Mouse    60 RETWSKKIDFLLSVIGFAVDLANVWRFPYLCYK--------NGGG-AFLVPYLLFMVIAGMPLFY 115

  Fly   141 IQAFLGQFSSSGTISAFRVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMSC 205
            ::..||||:..|....:::.|:.||:|:.::|::.....:|::.....|.|..:|....:||:.|
Mouse   116 MELALGQFNREGAAGVWKICPVLKGVGFTVILISFYVGFFYNVIIAWALHYFFSSFTMDLPWIHC 180

  Fly   206 NNSWNTQECS--------------------------------LHENYDVDDYRVDPHSTVEFFRS 238
            ||:||:..||                                ||::..:||..............
Mouse   181 NNTWNSPNCSDAHSSNSSDGLGLNDTFGTTPAAEYFERGVLHLHQSRGIDDLGPPRWQLTACLVL 245

  Fly   239 MIA----STAKG-STSMSISWSMLIGVLSIWLVVLALLLKPVAFIGKV--LRCSCVLMFGFFVAV 296
            :|.    |..|| .||..:.|   |.....::|:.||||:.|...|.:  :|.        :::|
Mouse   246 VIVLLYFSLWKGVKTSGKVVW---ITATMPYVVLTALLLRGVTLPGAMDGIRA--------YLSV 299

  Fly   297 FLYLLIHEQVTFDTLHYYWMPQLDSFDSILATARTALLMAGGALGPGWGSIITLSSYNNFRRDAE 361
            ..|.|....|..|                   |.|.:..   :||.|:|.:|..||||.|..:..
Mouse   300 DFYRLCEASVWID-------------------AATQVCF---SLGVGFGVLIAFSSYNKFTNNCY 342

  Fly   362 RLSIWVCLTHITIGLMGLLCCNVAHDHFEDHVGMMPLHVDEKHHMQFL-------YLCFSYLFGR 419
            |.:|      ||..:..|...:.....| ..:|.|.    :||::...       .|.|......
Mouse   343 RDAI------ITTSINSLTSFSSGFVVF-SFLGYMA----QKHNVPIRDVATDGPGLIFIIYPEA 396

  Fly   420 FTTTP--NLWAFLFFGMIFLSELCALIIQMMSVITALFDEFETLRSRRILVISSLVFCLTASSVY 482
            ..|.|  :.||.:||.|:....:.:.:..|.||||.|.|||:.|...|.|....:|......|::
Mouse   397 IATLPLSSAWAAVFFLMLLTLGIDSAMGGMESVITGLVDEFQLLHRHRELFTLGIVLATFLLSLF 461

  Fly   483 FCTQLGFSQLTQLPNLAVFTHLLISGILV--LMTTWVYGRVRFQCDLQFMLGKTISSFKIFFIRF 545
            ..|..|....|.|.:.|..|.:|. |:|:  :...|.||..:|..|::.|.|:..:.:.....:.
Mouse   462 CVTNGGIYVFTLLDHFAAGTSILF-GVLIEAIGVAWFYGVQQFSDDIKQMTGQRPNLYWRLCWKL 525

  Fly   546 ATPIFLGLCLFQLTYLFTRDRIHDVLIYV----SQGLILLTAISYMV-----YKVCRTNGDWRQR 601
            .:|.|| |.:..::.:..|...:...|:.    :.|.|:.|:...||     ||.|...|.:|::
Mouse   526 VSPCFL-LYVVVVSIVTFRPPHYGAYIFPDWANALGWIIATSSMAMVPIYATYKFCSLPGSFREK 589

  Fly   602 LQQCLAPH-DWHPVD-ADNRRF 621
            |...:.|. |...|| .:.|:|
Mouse   590 LAYAITPEKDRQLVDRGEVRQF 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_609140.2	SLC5-6-like_sbd	123..610	CDD:444915	133/546 (24%)
Slc6a3	NP_034150.1	SLC5-6-like_sbd	60..613	CDD:444915	148/607 (24%)
		Interaction with TGFB1I1. /evidence=ECO:0000250	560..589		10/28 (36%)