DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13796 and Slc6a20

DIOPT Version :9

Sequence 1:	NP_001137807.1	Gene:	CG13796 / 34051	FlyBaseID:	FBgn0031939	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	NP_579830.1	Gene:	Slc6a20 / 113918	RGDID:	621651	Length:	616	Species:	Rattus norvegicus

Alignment Length:	579	Identity:	120/579 - (20%)
Similarity:	228/579 - (39%)	Gaps:	145/579 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 DKCRGRWAKSADFYFASCTHAFSSLIFSELSTFGIL---HGGWLLFIIAYLMGMLFYSLPIFLIQ 142
            :|.|.:|.....|.||..::|..   ...:..|..|   :||. .|::.||:.::...:|:..::
  Rat    26 EKARPQWGNPLQFVFACISYAVG---LGNVWRFPYLCQMYGGG-SFLVPYLIMLIVEGMPLLYLE 86

  Fly   143 AFLGQFSSSGTISAFR-VAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMSCN 206
            ..:||....|:|.|:| ::|...|:|.|.::::.....||::.......|..:|....:||
  Rat    87 LAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWGFWYLFHSFQDPLPW---- 147

  Fly   207 NSWNTQECSLHENYDVDDYRVDPHSTVEFF--RSMIASTAKGSTSMSISWSMLIGVLSIWLVVLA 269
                 ..|.|:.|....|...:..|:.::|  |..:..:.....:..:.|...:.:...||:|..
  Rat   148 -----SVCPLNSNRTGYDEECEKASSTQYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLMVYL 207

  Fly   270 LLLKPVAFIGKVLRCSCVLMFGFFVAVFLY-LLIHEQVTFDTLH-------YYWMPQLDSFDSIL 326
            .:|:.....|||:         :|.|:..| :||...|...|||       |.:.|:::...:..
  Rat   208 CILRGTESTGKVV---------YFTALMPYCVLIIYLVRGLTLHGATNGLMYMFTPKIEQLANPK 263

  Fly   327 A--TARTALLMAGGALGPGWGSIITLSSYNNFRRDAERLSIWVCLTH---------ITIGLMGLL 380
            |  .|.|.:..   :||.|:||:|..:|||....|.::.::.|.:.:         :|..:.|.
  Rat   264 AWINAATQIFF---SLGLGFGSLIAFASYNEPSNDCQKHAVIVSVINSSTSIFASIVTFSIYGF- 324

  Fly   381 CCNVAHDHFEDHVGMMPLHVDEKHHMQFLYLCFS-------YLFGRFTTTPN------------- 425
               .|..::|:.:..:.|.:.....::..:|..|       ||   .:|.||
  Rat   325 ---KATFNYENCLNKVILLLTNSFDLEDGFLTASNLEEVKDYL---ASTYPNKYSEVFPHIRNCS 383

  Fly   426 ------------------------------LWAFLFFGMIFLSELCALIIQMMSVITALFDEFET 460
                                          ||:.|:|.|:.:..:.:::....:::|.|.|.
  Rat   384 LESELNTAVQGTGLAFIVYAEAIKNMEVSQLWSVLYFFMLLMLGMGSMLGNTAAILTPLTDS--- 445

  Fly   461 LRSRRILVISS-------------------LVFCLTASSVYFCTQLGFSQLTQLPNLAVFTHLLI 506
                  .||||                   :||.:.|.:.:|.....::        |..:.|||
  Rat   446 ------KVISSYLPKEAISGLVCLINCAVGMVFTMEAGNYWFDIFNDYA--------ATLSLLLI 496

  Fly   507 SGILVLMTTWVYGRVRFQCDLQFMLGKTISSFKIFFIRFATP-IFLGLCLFQLT-YLFT 563
            ..:..:...:|||..||:.||:.|.|:.::.:......|.:| :.:||.:|.|: |:.|
  Rat   497 VLVETIAVCYVYGLRRFESDLRAMTGRPLNWYWKAMWAFVSPLLIIGLFIFYLSDYILT 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_001137807.1	SLC5-6-like_sbd	123..610	CDD:294310	109/534 (20%)
Slc6a20	NP_579830.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26		120/579 (21%)
Slc6a20	NP_579830.1	SLC5-6-like_sbd	26..601	CDD:294310	120/579 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810