Protein Alignment CG13796 and Slc6a5

DIOPT Version :10

• Sequence 1: NP_609140.2
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_006540608.1
• Gene: Slc6a5 / 104245
• MGIID: 105090
• Length: 831
• Species: Mus musculus
• Alignment Length: 627
• Identity: 158/627 - (25%)
• Similarity: 255/627 - (40%)
• Gaps: 136/627 - (21%)

  Fly    81 DKCRGRWAKSADFYFASCTHA--------FSSLIFSELSTFGILHGGWLLFIIAYLMGMLFYSLP 137
            :|.||.|:...||..:...:|        |..|.|.        :||. .|:|.|||.:....||
Mouse   222 NKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQ--------NGGG-AFLIPYLMMLALAGLP 277

  Fly   138 IFLIQAFLGQFSSSGTISAFRVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPW 202
            ||.::..||||:|.|.:|.::..|..:|.|.|:|::::....||::.....|.|...|...|:||
Mouse   278 IFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPW 342

  Fly   203 MSCNNSWNTQECSLHENYDVDDYRVDPHSTVEFFRSMIASTAKGSTSM----------------- 250
            .||||.|||.||.......:|...:..|..::...|....||..:.:|
Mouse   343 GSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQTNKTFVSGSEE 407

  Fly   251 -----------------SISWSMLIGVLSIWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVAVFL 298
                             .|.|.:...:...|::|.|.|.|.:...|||:         :|.|.|.
Mouse   408 YFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKSSGKVV---------YFTATFP 463

  Fly   299 Y----LLIHEQVTFD----TLHYYWMPQLDSFD--SILATARTALLMAGGALGPGWGSIITLSSY 353
            |    :|:...||..    .:.|:..|:.:...  ::...|.|.:..   :|...||.:||||||
Mouse   464 YVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFF---SLSAAWGGLITLSSY 525

  Fly   354 NNFRRDAERLSIWV-CLTHITIGLMGLLCCNVAHDHFEDHVGMMPLHVDEKHHMQ--------FL 409
            |.|..:..|.::.| |....|....|.:..:|        :|.|.  .:.|.:::        ..
Mouse   526 NKFHNNCYRDTLIVTCTNSATSIFAGFVIFSV--------IGFMA--NERKVNIENVADQGPGIA 580

  Fly   410 YLCFSYLFGRFTTTPNLWAFLFFGMIFLSELCALIIQMMSVITALFDEF-ETLRSRRILVISSLV 473
            ::.:.....|...:| .||.:||.|:....|..:...:.:::|::.||| :.||:.:      .|
Mouse   581 FVVYPEALTRLPLSP-FWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHK------PV 638

  Fly   474 FCLTASSVYFCTQLGFSQLTQ--------LPNLAVFTHLLISGILVLM-TTWVYGRVRFQCDLQF 529
            |.|.....:|.  :||..:||        :...|....|:|..|..|: .::|||..||..|::.
Mouse   639 FTLGCCICFFI--MGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEM 701

  Fly   530 MLGKTISSFKIFFIRFATPIFLG--LC--LFQ---LTYLFTRDRIHDVLIYVSQGLI---LLTAI 584
            |:|...:.|......|.||..|.  ||  .:|   :||...|        |.:..::   |:.|.
Mouse   702 MIGFKPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYR--------YPNWSMVLGWLMLAC 758

  Fly   585 SYM------VYKVCRTNGDWRQRLQQCLAPH-DWHPVDADNR 619
            |.:      |.|:....|.:.:||:...:|. ||.|..|.:|
Mouse   759 SVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHR 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_609140.2	SLC5-6-like_sbd	123..610	CDD:444915	141/566 (25%)
Slc6a5	XP_006540608.1	SLC6sbd_GlyT2	225..821	CDD:271389	157/624 (25%)