Protein Alignment CG13796 and Slc6a8

DIOPT Version :10

• Sequence 1: NP_609140.2
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_598748.1
• Gene: Slc6a8 / 102857
• MGIID: 2147834
• Length: 640
• Species: Mus musculus
• Alignment Length: 691
• Identity: 153/691 - (22%)
• Similarity: 260/691 - (37%)
• Gaps: 175/691 - (25%)

  Fly    21 SEHGTELPGDFI-----GEPVETESGGGM---GGSLALAARRIRSRQVH------SMAVRTGSAY 71
            |..|.|..|..|     |.|.:.:...|:   ||.||:..|...:||:.      ..||..|:.:
Mouse    12 SVSGDEKKGPLIVSGPDGAPAKGDGPAGLGAPGGRLAVPPRETWTRQMDFIMSCVGFAVGLGNVW 76

  Fly    72 DTLERPYRHDKCRGRWAKSADFYFASCTHAFSSLIFSELSTFGILHGGWLLFIIAYLMGMLFYSL 136
                                         .|..|.:.        :||. :|:|.|::..|...:
Mouse    77 -----------------------------RFPYLCYK--------NGGG-VFLIPYVLIALVGGI 103

  Fly   137 PIFLIQAFLGQFSSSGTISAFRVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIP 201
            |||.::..||||..:|:|:.:.:.|:|||:|||.:::.....|||.:.......|.|.|....:|
Mouse   104 PIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLP 168

  Fly   202 WMSCNNSWNTQEC---SLHE--------NYDVDDYRVDPHSTVEFFRSMIASTAKG-STSMSISW 254
            |.:|.::|||.:|   ..||        |...|.........:||:.:.:...:.| ....:::|
Mouse   169 WATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSTGLEVPGALNW 233

  Fly   255 SMLIGVLSIWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVAVFLY-----LLIHEQV---TFDTL 311
            .:.:.:|:.|::|...:.|.|...||::         :|.|.|.|     ||:...:   ..|.:
Mouse   234 EVTLCLLACWVLVYFCVWKGVKSTGKIV---------YFTATFPYVVLVVLLVRGVLLPGALDGI 289

  Fly   312 HYYWMPQLDSFDS--ILATARTALLMAGGALGPGWGSIITLSSYNNFRRDAERLSIWVCLTH--- 371
            .||..|......|  :...|.|.:..   :...|.|::..|.|||.|..:..:.:|.:.|.:
Mouse   290 IYYLKPDWSKLGSPQVWIDAGTQIFF---SYAIGLGALTALGSYNRFNNNCYKDAIILALINSGT 351

  Fly   372 ------ITIGLMGLLCCNVAHDHFEDHVGMMPLHVDE--KHHMQFLYLCFSYLFGRFTTTPNLWA 428
                  :...::|.:...            ..:|:.:  :......::.:..........| |||
Mouse   352 SFFAGFVVFSILGFMATE------------QGVHISKVAESGPGLAFIAYPRAVTLMPVAP-LWA 403

  Fly   429 FLFFGMIFLSELCALIIQMMSVITALFDEFETLRSRRILVISSLVFCLTAS-SVYFCTQLGF--- 489
            .|||.|:.|..|.:..:.:...||.|.|          |:.:|..|..... ||..|..|.|
Mouse   404 ALFFFMLLLLGLDSQFVGVEGFITGLLD----------LLPASYYFRFQREISVALCCALCFVID 458

  Fly   490 -SQLTQLPN-------LAVFTHLLISGILVL--------MTTWVYGRVRFQCDLQFMLGKTISSF 538
             |.:|.:..       ..:|.:...||..:|        :..||||..||..|:..|:|.....:
Mouse   459 LSMVTDVSGGKGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPW 523

  Fly   539 KIFFIRFATP-IFLGLCLFQLTYLFTRDRIHDVLIYVS--------QGLILLTAISYMVYKVC-- 592
            ..:...|.|| :.:|:.:|.:.|       ::.|:|.:        :.:....|:|.|   :|
Mouse   524 MKWCWSFFTPLVCMGIFIFNIVY-------YEPLVYNNTYVYPWWGEAMGWAFALSSM---LCVP 578

  Fly   593 --------RTNGDWRQRLQQCLAP-----H-DWHPVDADNR 619
                    |..|...:|.|....|     | ::...|||.|
Mouse   579 LHLLGCLLRAKGTMAERWQHLTQPIWGLHHLEYRAQDADVR 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_609140.2	SLC5-6-like_sbd	123..610	CDD:444915	127/564 (23%)
Slc6a8	NP_598748.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		5/14 (36%)
		SLC6sbd_CT1	52..626	CDD:271397	141/651 (22%)