Protein Alignment CG13796 and slc6a4

DIOPT Version :9

• Sequence 1: NP_001137807.1
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_017946918.1
• Gene: slc6a4 / 100493853
• XenbaseID: XB-GENE-22062972
• Length: 664
• Species: Xenopus tropicalis
• Alignment Length: 676
• Identity: 168/676 - (24%)
• Similarity: 280/676 - (41%)
• Gaps: 132/676 - (19%)

  Fly     6 GEQLNNC---MLLGDCENSEHGTELPGDFIGEP---------VET--------ESGGGMGGSLAL 50
            |:.|.||   :.|.:..|..|.:  ||: .|||         |::        .:||..|.:..|
 Frog    32 GQLLRNCKPSLRLSEELNKVHPS--PGE-RGEPGHISNKYLAVQSPEAPCNGMRNGGDEGSTPTL 93

  Fly    51 AARRIRSRQVHSMAVRTGSAYDTLERPYRHDKCRGRWAKSADFYFASCTHA--------FSSLIF 107
            ........::..:....|.              |..|:|..||..:...:|        |..:.:
 Frog    94 TVLPACRAEIQHLQTEIGE--------------RETWSKKIDFLLSVIGYAVDLGNVWRFPYVCY 144

  Fly   108 SELSTFGILHGGWLLFIIAYLMGMLFYSLPIFLIQAFLGQFSSSGTISAFR-VAPIFKGIGYAIL 171
            .        :||. .|:|.|::..:|..:|:|.::..:||:..:|.||.:| :.|:||||||||.
 Frog   145 Q--------NGGG-AFLIPYVIMAVFGGIPLFYMELAMGQYHRNGCISIWRKICPLFKGIGYAIC 200

  Fly   172 LLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMSCNNSWNTQECSLH-ENYDV--DDYRVDPHSTV 233
            ::.|....||:......|.|.:.|....:||.||.|.|||..|:.: :|..|  .:..:.|  ..
 Frog   201 MIALYVAFYYNTIMAWALYYLIFSFRSELPWTSCLNEWNTGNCTNYFQNSSVGWSNSSISP--AE 263

  Fly   234 EFFRSMIAS--TAKGSTSM-SISWSMLIGVLSIWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVA 295
            ||:..::..  .:||...: .|||.:.:.:|.|:.||...:.|.|...|||     |.:...|..
 Frog   264 EFYTRLVLQIHKSKGLHDLGGISWQLTLCLLLIFTVVYFSIWKGVKTSGKV-----VWVTATFPY 323

  Fly   296 VFLYLLIHEQVT----FDTLHYYWMPQLDSFDSILATA--RTALLMAGGALGPGWGSIITLSSYN 354
            :.|.||:....|    :..:.:|..|   .::.:|.||  ..|......:||||:|.::..:|||
 Frog   324 IVLALLLIRGATLPGAWRGVLFYLQP---DWEKLLTTAVWVDAAAQIFFSLGPGFGVLLAFASYN 385

  Fly   355 NFR----RDAERLSIWVCLTHITIGL-----MGLLCCNVAHDHFEDHVGMMPLHVDE---KHHMQ 407
            .|.    :||...|...|:|....||     :|.:            ..|..|.|.|   .....
 Frog   386 KFHNNCYQDALITSTVNCMTSFMSGLVIFTVLGYM------------AEMRNLDVSEVAKDTGPS 438

  Fly   408 FLYLCFSYLFGRFTTTPNLWAFLFFGMIFLSELCALIIQMMSVITALFDEFETLRSRR----ILV 468
            .|::.::........: ..:|.:||.|:....|.:....:..||||:.|||..:..:|    :.:
 Frog   439 LLFITYAEAIANMPAS-TFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHIWGKRRELFVFL 502

  Fly   469 ISSLVFCLTASSVYFCTQLGFSQLTQL-----PNLAVFTHLLISGILVLMTTWVYGRVRFQCDLQ 528
            :.|:.|....|::.|    |.:.:.:|     ...||.|.:.:..|.|   :|.||..:|..|::
 Frog   503 LISVCFLGALSTLTF----GGAYMVKLFEEYATGPAVLTVVFLEAIAV---SWFYGINQFCRDVR 560

  Fly   529 FMLGKTISSF-KIFFIRFATPIFL--GLCLFQ--------LTYLFTRDRIHDVLIYVSQGLILLT 582
            .|||.:...| ||.::... |:||  .:|.|.        ..|.:....:  ||.|.......:.
 Frog   561 EMLGFSPGWFWKICWVAIC-PLFLLFIICSFMSSPPDLRLFNYQYPSWTV--VLGYCIGTSSFIC 622

  Fly   583 AISYMVYKVCRTNGDWRQRLQQCLAP 608
            ..:||||.:..|.|..::|..:.:.|
 Frog   623 VPAYMVYLLTSTPGSIKERFLKSITP 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_001137807.1	SLC5-6-like_sbd	123..610	CDD:294310	141/531 (27%)
slc6a4	XP_017946918.1	5HT_transport_N	48..91	CDD:367522	11/45 (24%)
		SLC5-6-like_sbd	113..649	CDD:382020	150/578 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010