DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13796 and slc6a7

DIOPT Version :9

Sequence 1:	NP_001137807.1	Gene:	CG13796 / 34051	FlyBaseID:	FBgn0031939	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	XP_002940131.3	Gene:	slc6a7 / 100487063	XenbaseID:	XB-GENE-479449	Length:	634	Species:	Xenopus tropicalis

Alignment Length:	612	Identity:	157/612 - (25%)
Similarity:	255/612 - (41%)	Gaps:	113/612 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 DTLERPYRHDKCRGRWAKSADFYFASCTHAFSSLIFSELSTFGILHG--------------GWLL 122
            |..|....:.:.||.|:...||.               ||..|...|              |...
Frog    25 DDTELDIEYPEDRGNWSGKLDFL---------------LSCIGYCVGLGNVWRFPYRAYTNGGGA 74

  Fly   123 FIIAYLMGMLFYSLPIFLIQAFLGQFSSSGTISAFRVAPIFKGIGYAILLLNLGTLTYYSIAAVV 187
            |:|.|.:.:....:|:|.::..||||||.|.::.::::|:|||:|..:||:......||::....
Frog    75 FLIPYFIMLAICGIPLFFMELSLGQFSSLGPLAVWKISPLFKGVGMGMLLIVALVAIYYNMIIAY 139

  Fly   188 PLIYTVNSIHPVIPWMSCNNSWNTQECSLHENYDVDD--YRVDPHSTV---EFFRSMIASTAKGS 247
            .|.|...|:...:||..|.|.|||..|..|......:  ..|:..:||   |.:.|......:||
Frog   140 VLFYLFASLTSSLPWEHCGNWWNTDLCLDHHVIRASNSALLVNISNTVSPSEEYWSRYVLHIQGS 204

  Fly   248 TSM----SISWSMLIGVLSIWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVAVFLY----LLIHE 304
            :.:    .:.|.:.:.:|..|.:|...:||.|...|||:         :|.|.|.|    :|:..
Frog   205 SGIGDPGQLRWKLCLCLLLSWTIVYLCILKGVKSSGKVV---------YFTATFPYIILVMLLIR 260

  Fly   305 QVTFD----TLHYYWMPQLDSFDSILATART---ALLMAGGALGPGWGSIITLSSYNNFRRDAER 362
            .||.:    .:.:|..||.:.    |.|::.   |.|....:||.|:|.::|.:|||.|.::..|
Frog   261 GVTLEGAWIGIKFYLTPQFEH----LLTSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYR 321

  Fly   363 LSIWVCLTH-ITIGLMGLLCCNVAHDHFEDHVGMMPLHVDEKHHMQFLYLCFSYLFGRFTTTPNL 426
            .:..|.|.: .|..|.|....:|. .:....:| :|:....|......::.:.........:| .
Frog   322 DTFIVTLGNAFTSILAGFAIFSVL-GYMSQELG-VPVDQVAKAGPGLAFVVYPQAMTMLPLSP-F 383

  Fly   427 WAFLFFGMIFLSELCALIIQMMSVITALFDEFE-TLRSRRILVISSLVFCLTASSVYFCTQLGFS 490
            |:||||.|:....|.:....|.:::||:.|||. .||.::.:..:.:...|....:...|..|..
Frog   384 WSFLFFFMLLTLGLDSQFAFMETIVTAITDEFPYYLRPKKAVFSAIICVALFLLGLILATDGGMY 448

  Fly   491 QLTQLPNL-AVFTHLLISGILVLMTTW------VYGRVRFQCDLQFMLG-KTISSFKIFFIRFAT 547
            .|..|.:. |.|      |:||::.|:      |||...|..|:|.||| |....||..:| |.:
Frog   449 WLVLLDDYSAGF------GLLVIVITFCLSVSRVYGIKNFCRDIQMMLGFKPGLYFKACWI-FLS 506

  Fly   548 PIFLGLCLFQLTYLFTRDRIHDVLIY------------------VSQGLILLTAISY-MVYKVCR 593
            |:.| :||  |.|        .:|.|                  :..||:....|.. |:..:.:
Frog   507 PVTL-MCL--LAY--------SILKYQPSQYGSYKFPLWSEALGILMGLLSCMMIPIGMLVAILK 560

  Fly   594 TNGDWRQRLQQCLAP-HDWHPVDADNR 619
            ..|...:|::|...| .||.|...:||
Frog   561 EEGSLWERIRQASRPAMDWGPSMEENR 587

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_001137807.1	SLC5-6-like_sbd	123..610	CDD:294310	140/536 (26%)
slc6a7	XP_002940131.3	SLC5-6-like_sbd	37..581	CDD:382020	152/592 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010