Protein Alignment CG13796 and slc6a2

DIOPT Version :10

• Sequence 1: NP_609140.2
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_017948962.2
• Gene: slc6a2 / 100486589
• XenbaseID: XB-GENE-486549
• Length: 624
• Species: Xenopus tropicalis
• Alignment Length: 607
• Identity: 148/607 - (24%)
• Similarity: 258/607 - (42%)
• Gaps: 104/607 - (17%)

  Fly    75 ERPYRHDKCRGRWAKSADFYFASCTHAFSSLIFSELSTFGIL---HGGWLLFIIAYLMGMLFYSL 136
            |.|....:.|.:|.|..||..:....   |:..:.:..|..|   :||. .|:|.|.:.::...:
 Frog    54 EVPGEGQQEREQWGKKIDFLLSVVGF---SVDLANVWRFPFLCYKNGGG-AFLIPYTLFLIIAGM 114

  Fly   137 PIFLIQAFLGQFSSSGTISAFRVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIP 201
            |:|.::..|||::..|..:.:::.|:|||:||.::|:.|....||::.....|.|.|:|....:|
 Frog   115 PLFYMELALGQYNREGAATVWKICPLFKGVGYTVILIALYVGFYYNVIIAWSLYYLVSSFTSELP 179

  Fly   202 WMSCNNSWNTQECS---------LHENYDVDDYRVDPHSTVEFFRSMIASTAKGSTSMSIS---W 254
            |:.|.|.||:..|:         :..|.....::..|  ..||:...:....:.:....:.   |
 Frog   180 WIKCGNEWNSLNCTDPMLLNMSMISYNTKYSKFKTTP--AAEFYERGVLHLHESNGIHDLGQPRW 242

  Fly   255 SMLIGVLSIWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVAVFLYLLIHEQVTFD--------TL 311
            .:.|.::.:.:|:...|.|.|...|||:..:..|.:     |.|::|:...:|..        .|
 Frog   243 QLTICLIVVLIVLFFSLWKGVKTSGKVVWITATLPY-----VVLFVLLIRGITLPGSSKGISAYL 302

  Fly   312 HYYWMPQLDSFDSILATARTALLMAGGALGPGWGSIITLSSYNNF----RRDAERLSIWVCLTHI 372
            |.......|:  |:...|.|.:..   :||.|:|.:|..:|||.|    .|||...|...|:|..
 Frog   303 HIDIKRLTDA--SVWIDAATQIFY---SLGAGFGVLIAFASYNKFDNNCYRDALMTSTINCVTSF 362

  Fly   373 TIG-----LMGLLCCNVAHDH---FED----HVGMMPLHVDEKHHMQFLYLCFSYLFGRFTTTPN 425
            ..|     ::|.:    ||.|   .||    ..|::.:...|         ..|.|.|     ..
 Frog   363 ISGFAIFSILGYM----AHKHNVNIEDVATEGAGLVFIIYPE---------AISTLAG-----ST 409

  Fly   426 LWAFLFFGMIFLSELCALIIQMMSVITALFDEFETLRSRR---ILVISSLVF-----CLTASSVY 482
            .||.:||.|:....:.:.:..|.:|||.|.|:...|:..|   .|:::.:.|     |:|...:|
 Frog   410 FWAVVFFIMLLTLGIDSAMGGMEAVITGLADDISILKRHRKLFTLLVAFITFIFALLCITNGGIY 474

  Fly   483 FCTQLGFSQLTQLPNLAVFTHLLISGIL-VLMTTWVYGRVRFQCDLQFMLGKTISSFKIFFIRFA 546
            .        ||.|...|..|.:|.:.:: .:..:|.||..||..|:..|||.....:.....:|.
 Frog   475 V--------LTLLDTFAAGTSILFAVLIEAIGVSWFYGVDRFSEDIHRMLGFRPGLYWRLCWKFV 531

  Fly   547 TPIFLGLCLFQLTYLFTRDRIHDVLIY----------VSQGLILLTAISYMVYKVCRTNGDWRQR 601
            :|.|| |.:..::.:..:..::|...:          ::...:.|..| |::||.....|..|:|
 Frog   532 SPAFL-LFVVIVSIVTYKPLMYDEYKFPPWANRTGWAIALSSMTLVPI-YIIYKFLTMRGSLRER 594

  Fly   602 LQQCLAPHDWHPVDA--DNRRF 621
            |..|:.|.:.|.:.|  |.|:|
 Frog   595 LAYCITPENEHHLVAQGDIRQF 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_609140.2	SLC5-6-like_sbd	123..610	CDD:444915	131/541 (24%)
slc6a2	XP_017948962.2	SLC5-6-like_sbd	63..622	CDD:444915	146/598 (24%)