DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13796 and slc6a15

DIOPT Version :9

Sequence 1:	NP_001137807.1	Gene:	CG13796 / 34051	FlyBaseID:	FBgn0031939	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	XP_002931668.1	Gene:	slc6a15 / 100380162	XenbaseID:	XB-GENE-975885	Length:	730	Species:	Xenopus tropicalis

Alignment Length:	622	Identity:	133/622 - (21%)
Similarity:	236/622 - (37%)	Gaps:	139/622 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ELPGDFIGEPVETESGGGMGGSLALAARRIRSRQV-HSMAVRTGSAYDTLERPYRHDKCRGRWAK 89
            ||..||:....:..|....|......:..:.|..| ....:..||..|. |||        .|..
Frog    11 ELDDDFVESVKDLLSNEDSGDESFKKSELVVSDDVDKDRDIEEGSDIDD-ERP--------AWNS 66

  Fly    90 SADFYFASCTHAFSSLIFSELSTFGIL---HGGWLLFIIAYLMGMLFYSLPIFLIQAFLGQFSSS 151
            ...:..|....   |:....:..|..|   :||. .:::.||:.:|...:|:|.::..:||....
Frog    67 KLQYILAQVGF---SVGLGNVWRFPYLCQKNGGG-AYLVPYLILLLLIGIPVFFLELSVGQRIRR 127

  Fly   152 GTISAFR-VAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMSC---NNSWNT- 211
            |:|..:. ::|...|||:|..::.|....||::.....|.|...|....:||..|   .|:.||
Frog   128 GSIGVWNYISPKMGGIGFASCIVCLFVALYYNVIIGWSLFYFSQSFQHPLPWDQCPLVKNASNTF 192

  Fly   212 --QECSLHENYDVDDYRVDPHSTVEFFRSMIASTAKGSTSMSISWSMLIGVLSIWLVVLALLLKP 274
              .||           .....:|..::|..:..:...:....::|.|.:.:|:.|::|...::|.
Frog   193 VEPEC-----------EKSSATTYYWYREALNISNSITEGGGLNWKMTLCLLAAWILVCLAMIKG 246

  Fly   275 VAFIGKVLRCSCVLMFGFFVAVFLY----------LLIHEQVTFDTLHYYWMPQLDSF--DSILA 327
            :...|||:         :|.::|.|          ||::..|  |.:.:.:.|:|:..  ..:..
Frog   247 IQSSGKVM---------YFSSLFPYVVLTCFLVRALLLNGSV--DGIRHMFTPKLEIMLEPKVWR 300

  Fly   328 TARTALLMAGGALGPGWGSIITLSSY----NNFRRDAERLSI-----WVCLTHITIGLMG----- 378
            .|.|.:..   |||.|:|.:|..|||    ||...||..:|.     .|..|.:...::|
Frog   301 EAATQVFF---ALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANI 362

  Fly   379 ---------------------LLCCNVAH------------------------DHFEDHVGMMPL 398
                                 |...||.|                        :.| |.:|:...
Frog   363 MNENCISKNTVKIVKYLEAGNLSWSNVPHHVNFSSMSAQDYNLVYYIFQKIKEEEF-DSLGLDSC 426

  Fly   399 HVDEKHHMQ-----FLYLCFSYLFGRFTTTPNLWAFLFFGMIFLSELCALIIQMMSVITALFDEF 458
            .::::.:..     ..::.|:.....|..:| .|:.:||.|:....|.::...:..:||.:.|.|
Frog   427 QIEDELNKSVQGTGLAFIAFTEAMTHFPASP-FWSVMFFLMLVNLGLGSMFGTIEGIITPIVDTF 490

  Fly   459 ETLRSRRILVISSLVFCL-----TASSVYFCTQLGFSQLTQLPNLAVFTHLLISGILVLMTTWVY 518
            :..:....:....|.||:     ..|..||.|.......| ||.|.|   :::..:.:   .|||
Frog   491 KVRKEPLTVGCCLLAFCIGLLFVQRSGNYFVTMFDDYSAT-LPLLIV---VILENVAI---AWVY 548

  Fly   519 GRVRFQCDLQFMLGKTISSFKIFFIRFATPIFLGLCL 555
            |..:|..||:.|||.|...:..:..::.:|:.|.:.|
Frog   549 GIDKFMDDLKDMLGFTPYKYYYYMWKYISPVLLTILL 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_001137807.1	SLC5-6-like_sbd	123..610	CDD:294310	112/521 (21%)
slc6a15	XP_002931668.1	SLC5-6-like_sbd	61..640	CDD:382020	121/571 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920