DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13796 and si:ch211-132b12.3

DIOPT Version :9

Sequence 1:	NP_001137807.1	Gene:	CG13796 / 34051	FlyBaseID:	FBgn0031939	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	NP_001076419.1	Gene:	si:ch211-132b12.3 / 100002232	ZFINID:	ZDB-GENE-050419-161	Length:	577	Species:	Danio rerio

Alignment Length:	593	Identity:	142/593 - (23%)
Similarity:	241/593 - (40%)	Gaps:	121/593 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 RGRWAKSADFYFASCTHA--------FSSLIFSELSTFGILHGGWLLFIIAYLMGMLFYSLPIFL 140
            ||.|.:.|:|..|...:.        |..|.:.        :||. :|:|.||:.::...:|:||
Zfish    11 RGFWGRKAEFLLAVAGNVVGVGNVWRFPYLCYR--------NGGG-VFLIPYLVFVMTCGVPLFL 66

  Fly   141 IQAFLGQFSSSGTISAFR-VAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMS 204
            ::..:|||:..|.|:.:. :.|:.:|:|||..|:.|.:..|::|.....|.|.:.|....:||.|
Zfish    67 LETVMGQFTHEGGITCWHLLCPLAQGVGYAGQLIELYSCMYFTIILAWALFYLIFSFSSQLPWAS 131

  Fly   205 CNNSWNTQEC--------SLHENYDVDDYRVDPHSTVEFFRSMIASTAKGSTSM-SISWSMLIGV 260
            |:|.|||..|        :.:....::    ...:..||:...:.|.:.|...: .|:|.:.:.:
Zfish   132 CDNIWNTDNCVNLAAGNLTFNRTTQIN----STSAATEFWERRVLSLSGGIEEIGKINWEIALCL 192

  Fly   261 LSIWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVAVFLY-----LLIH--------EQVTFDTLH 312
            ..:|::....:.|.|...|||:         :|.|.|.|     |||.        :.|.|   :
Zfish   193 FVMWIICYFCIWKGVKSTGKVV---------YFTATFPYVMLLVLLIRGLTLPGALQGVVF---Y 245

  Fly   313 YYWMPQLDSFDSILATARTALLMAGGALGPGWGSIITLSSYNNFRRDAERLSIWVCLTHI-TIGL 376
            .|..|...:...:...|.|.:..:.....   |.:|.|.|||.:..:..|.|.|:||.:. |..:
Zfish   246 LYPEPAHLADPQVWMEAGTQVFFSYSLCS---GILIALGSYNQYSNNCYRDSFWLCLLNSGTSFV 307

  Fly   377 MGLLCCNVAHDHFEDHVGMMPLHVDEKHHMQFLYLCFSYLFGRFTTTPNLWAFLFFGMIFLSELC 441
            .|....:|.  .|..||..:|:....:......::.:..... ....|.|||..||.||.|..|.
Zfish   308 AGFAVFSVL--GFMAHVQGVPVEEVAESGPGLAFIAYPQAVA-MMPFPQLWAVCFFIMIILLGLD 369

  Fly   442 ALIIQMMSVITALFDEF-ETLR--SRRILVISSLVFCLTA--SSVYFCTQLGFSQLTQLPN---- 497
            :..:.|..|:|::.|.| |.||  .||.|.:  |:.|||.  ..:...|:.|........|
Zfish   370 SQFVAMECVVTSVTDLFPEVLRRAGRRELFV--LLLCLTCFFGQLIMVTEGGMYVFQLFDNYASN 432

  Fly   498 ------LAVFTHLLISGILVLMTTWVYGRVRF----------QCDLQFMLG-------KTISSFK 539
                  |:||..|.|.        |::|..:.          :.:..|||.       .:::||.
Zfish   433 GACFLFLSVFESLTIG--------WIFGAEKMFDIIKDMTESRPNYWFMLCWKYLTPLVSLTSFV 489

  Fly   540 IFFIRFATPIFLGLCLFQLTYLFTRDRIHDVLIYVSQGLILLTAI----SYMVYKVCRTNGDWRQ 600
            ...:|: ||         |||  .|..::....:|...|:.|::|    .:.:.::|...|..:|
Zfish   490 YSMVRY-TP---------LTY--NRWYVYPDWAHVLGWLLALSSILLVPGWALGQMCTGKGSLKQ 542

  Fly   601 RLQQCLAP 608
            |.....:|
Zfish   543 RWGHLCSP 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_001137807.1	SLC5-6-like_sbd	123..610	CDD:294310	132/546 (24%)
si:ch211-132b12.3	NP_001076419.1	SLC6sbd-TauT-like	11..550	CDD:271387	141/591 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920