Protein Alignment CG13795 and Slc6a2

DIOPT Version :10

• Sequence 1: NP_609138.3
• Gene: CG13795 / 34049
• FlyBaseID: FBgn0031937
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_112633.2
• Gene: Slc6a2 / 83511
• RGDID: 621822
• Length: 617
• Species: Rattus norvegicus
• Alignment Length: 600
• Identity: 142/600 - (23%)
• Similarity: 265/600 - (44%)
• Gaps: 73/600 - (12%)

  Fly    20 RGKWDKPTDFMFACFGLALKLDVFVASFWMF-----FDMGILGILPYFVYMSIYLVPIMVIHSFM 79
            |..|.|..||:.:..|.|:.|    |:.|.|     .:.|...::||.:::.|..:|:..:...:
  Rat    56 RETWGKKIDFLLSVVGFAVDL----ANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELAL 116

  Fly    80 GQFSSSGFISAFRLSPFFKGMGYVSGFLTISMLIYYSIFAAVPLLFIINSFRPTLPWSCEGLSSW 144
            |||:..|..:.:::.|||||:||....:.:.:..||::..|..|.::..||...|||:..| .:|
  Rat   117 GQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCG-HAW 180

  Fly   145 HNGSATLSSSCNKTLILEDFSEYNRSHQLLHVPSVLYFQN-----HYDSMQQD-AVPDWYKDYEL 203
            ::.:.|.....|.: :|.|.::|::   ....|:..:::.     |..|...| .:|.|.
  Rat   181 NSPNCTDPKLLNAS-VLGDHTKYSK---YKFTPAAEFYERGVLHLHESSGIHDIGLPQWQ----- 236

  Fly   204 SWHFVGLFAIIWVVIAFIFYKFSETAK-FGKLIRYMVIVTLVLLLVCFVRFLFLPGALNGLHRYV 267
                  |...:.|||..:::...:..| .||::.....:...:|.|..|..:.||||.||::.|:
  Rat   237 ------LLLCLMVVIVVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYL 295

  Fly   268 TPKASDMAMGVV--STFIMVLHAFGAGWGSVITLSSFNGFKTD-------IMSYSWIISFGQIFI 323
            ......:....|  .....:..:.|||:|.:|..:|:|.|..:       ..:.:.:.||  |..
  Rat   296 HIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSF--ISG 358

  Fly   324 YIMFGMVSFMLEHYFNELSDVDDNGHVLSHWLLYLSSASALSTMAWPNLWTFIYYSMLLIAALIV 388
            :.:|.::.:|...:..::.||...|    ..|:::....|:||::....|..:::.|||...|..
  Rat   359 FAIFSILGYMAHEHKVKIEDVATEG----AGLVFVLYPEAISTLSGSTFWAVLFFLMLLALGLDS 419

  Fly   389 MTTQIFTVLQSLFDEFEVLRVRKQEVTFGLIGGIALCSFYFCTNHGIIFFSALGLDAIFSHSLLH 453
            ....:..|:..|.|:|:||:..::..|..:..|..|.:.:..|..||...:.|...|..:..|..
  Rat   420 SMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLTLLDTFAAGTSILFA 484

  Fly   454 LLLLLV-VLWIYGRERFQRDIEFMLG-QPFASWKVFILRFIAPIILVICLLAGI----ALSISEH 512
            :|:..: |.|.||.:||..||:.|:| :|...|:: ..:|::|..|:..::..|    .|:..::
  Rat   485 VLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRL-CWKFVSPAFLLFVVVVSIINFKPLTYDDY 548

  Fly   513 SYSTTV------VFVMSIVLVVLPILAIPGYGFYYLYQSTGTFCERFKRTCRPTDWYPVEMEHRQ 571
            .|....      :.:.|::||       |.|..|..:...|:..||......|      |.||..
  Rat   549 VYPPWANWVGWGIALSSMILV-------PAYVIYKFFSIRGSLWERVAYGITP------ENEHHL 600

  Fly   572 QYEEAVDNTEMTHQL 586
            ..:..|...::.|.|
  Rat   601 VAQRDVRQFQLRHWL 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13795	NP_609138.3	SLC5-6-like_sbd	27..505	CDD:271356	120/500 (24%)
Slc6a2	NP_112633.2	SLC5-6-like_sbd	56..615	CDD:444915	141/598 (24%)