Protein Alignment CG13795 and SLC6A20

DIOPT Version :10

• Sequence 1: NP_609138.3
• Gene: CG13795 / 34049
• FlyBaseID: FBgn0031937
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001372612.1
• Gene: SLC6A20 / 54716
• HGNCID: 30927
• Length: 603
• Species: Homo sapiens
• Alignment Length: 654
• Identity: 137/654 - (20%)
• Similarity: 250/654 - (38%)
• Gaps: 187/654 - (28%)

  Fly    20 RGKWDKPTDFMFACFGLALKLDVFVASFWMF------FDMGILGILPYFVYMSIYLVPIMVIHSF 78
            |..|.....|:|||...|:.|    .:.|.|      :..|.. ::||.:.:.:..:|::.:...
Human     5 RPLWANSLQFVFACISYAVGL----GNVWRFPYLCQMYGGGSF-LVPYIIMLIVEGMPLLYLELA 64

  Fly    79 MGQFSSSGFISAFR-LSPFFKGMGYVSGFLTISMLIYYSIFAAVPLLFIINSFRPTLPWSCEGLS 142
            :||....|.|.|:| :||:..|:|..|..::..:.:||::..|....::.:||:..||||...|:
Human    65 VGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVCPLN 129

  Fly   143 SWHNGSATLSSSCNKTLILEDFSEYNRSHQLLHVPSVLYFQNHYDSMQQDAVPDWY-KDYELS-- 204
            ..|.|   ....|.|                  ..|..||              || |...:|
Human   130 GNHTG---YDEECEK------------------ASSTQYF--------------WYRKTLNISPS 159

  Fly   205 --------WHFVGLFAIIWVVIAFIFYKFSETAKFGKLIRYMVIVTLVLLLVCFVRFLFLPGALN 261
                    |.......:.|:|:.....:.:|:.  ||::.:...:...:|::..:|.|.|.||.|
Human   160 LQENGGVQWEPALCLLLAWLVVYLCILRGTEST--GKVVYFTASLPYCVLIIYLIRGLTLHGATN 222

  Fly   262 GLHRYVTPKASD----MAMGV---------VSTFIMVLHAFGAGWGSVITLSSFNGFKTDIMSYS 313
            ||....|||.|.    :|..:         ::....:..:.|.|:||:|..:|:|....:...::
Human   223 GLMYMFTPKGSSALSLLAFQIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHA 287

  Fly   314 WIIS--------FGQIFIYIMFGM------------VSFMLEHYFNELSDVDD-----------N 347
            .|:|        |..|..:.::|.            ||.:|.:.|    |::|           .
Human   288 IIVSLINSFTSIFASIVTFSIYGFKATFNYENCLKKVSLLLTNTF----DLEDGFLTASNLEQVK 348

  Fly   348 GHVLSHW----------------------------LLYLSSASALSTMAWPNLWTFIYYSMLLIA 384
            |::.|.:                            |.::....|:..|....||:.:|:.|||:.
Human   349 GYLASAYPSKYSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLML 413

  Fly   385 ALIVMTTQIFTVLQSLFDEFEVLRVRKQEVTFGLIGGIALCSFYFCTNHGIIFFSALG---LDAI 446
            .:..|......:|..|.|...:.....:|...||: .:..|:.      |::|....|   .| |
Human   414 GIGSMLGNTAAILTPLTDSKIISSHLPKEAISGLV-CLVNCAI------GMVFTMEAGNYWFD-I 470

  Fly   447 FSHSLLHLLLLLVVL-------WIYGRERFQRDIEFMLGQPFA-SWKVFILRFIAPIILVICLLA 503
            |:.....|.|||:||       ::||..||:.|::.|.|:..: .||| :...::|:::|...:
Human   471 FNDYAATLSLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKV-MWAGVSPLLIVSLFV- 533

  Fly   504 GIALSISEHSYSTTV------------------VFVMSIV--LVVLPILAIPGYGFYYLYQSTGT 548
               ..:|::..:.|:                  .:.::::  ||....:.||       ..:.||
Human   534 ---FYLSDYILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIP-------LAALGT 588

  Fly   549 FCER 552
            |.:|
Human   589 FVQR 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13795	NP_609138.3	SLC5-6-like_sbd	27..505	CDD:271356	125/578 (22%)
SLC6A20	NP_001372612.1	SLC6sbd_SIT1	2..588	CDD:271401	133/648 (21%)