Protein Alignment CG13795 and slc6a5

DIOPT Version :10

• Sequence 1: NP_609138.3
• Gene: CG13795 / 34049
• FlyBaseID: FBgn0031937
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001009557.1
• Gene: slc6a5 / 494450
• ZFINID: ZDB-GENE-050105-2
• Length: 786
• Species: Danio rerio
• Alignment Length: 620
• Identity: 151/620 - (24%)
• Similarity: 279/620 - (45%)
• Gaps: 94/620 - (15%)

  Fly    20 RGKWDKPTDFMFACFGLALKL-DVFVASFWMFFDMGILGILPYFVYMSIYLVPIMVIHSFMGQFS 83
            ||.|....||:.:..|.|:.| :|:...:..|.:.|...::||.:.:.:..:||.::...:|||:
Zfish   177 RGNWSNKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLIMLGLAGIPIFLLEVSLGQFA 241

  Fly    84 SSGFISAFRLSPFFKGMGYVSGFLTISMLIYYSIFAAVPLLFIINSFRPTLPWS----------C 138
            |.|.:|.::..|..:|.|.....:::.:.|||:|.....|.::..|.:.||||:          |
Zfish   242 SQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNIIMCWTLYYLFASLKETLPWATCKNEWNTVEC 306

  Fly   139 E---------------GLSSWHNGSATLSSSC-------------NKTLI--LEDFSEYNRSHQL 173
            :               .::|..|.:..||::.             |||.:  .|::.:||    :
Zfish   307 KDKDMLLLDTCILRDRNITSIKNTTFCLSANVVGNLSKLLNVTVDNKTYVSPSEEYFKYN----V 367

  Fly   174 LHVPSVLYFQNHYDSMQQDAVPDWYKDYELSWHFVGLFAIIWVVIAFIFYKFSETAK----FGKL 234
            ||:...:.:..                 ::.|.......:.|:::      ::..||    .||:
Zfish   368 LHISKGIEYPG-----------------DIRWPLAACLFLAWLIV------YASLAKGIKSSGKV 409

  Fly   235 IRYMVIVTLVLLLVCFVRFLFLPGALNGLHRYVTPKASDMAMGVV--STFIMVLHAFGAGWGSVI 297
            :.:......|:|::..:|.:.||||.:|:..::|||...:....|  .....:..:..|.||.:|
Zfish   410 VYFTATFPYVVLVILLIRGVTLPGAGSGILYFITPKWEKLNDAKVWKDAATQIFFSLSAAWGGLI 474

  Fly   298 TLSSFNGFKTDIMSYSWII----SFGQIFI-YIMFGMVSFMLEHYFNELSDVDDNGHVLSHWLLY 357
            ||||:|.|..:....:.|:    |...||. :::|.::.||.......:..|.|.|..:: :::|
Zfish   475 TLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMAHELKVPIESVADEGPGIA-FVVY 538

  Fly   358 LSSASALSTMAWPNLWTFIYYSMLLIAALIVMTTQIFTVLQSLFDEF-EVLRVRKQEVTFGLIGG 421
               ..||:.:.....|..|::.|||...|..|...|.|::.|:.||| :.||..|.:.|......
Zfish   539 ---PEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSVSDEFPKYLRKHKPQFTLVCCLS 600

  Fly   422 IALCSFYFCTNHGIIFFSALGLDAIFSHSLLHLLL--LLVVLWIYGRERFQRDIEFMLG-QPFAS 483
            ..:..|...|..|:.....:...|. |:||:.:.:  |:.:.:|||.:||..|||.|:| ||...
Zfish   601 FFVLGFPMITESGMYMLQLVDTFAA-SYSLVIIAIFELVGISYIYGLQRFCEDIEMMIGFQPNKF 664

  Fly   484 WKV---FILRFIAPIILVICLLAGIALSISEHSYSTTVVFVMSIVLVVLPILAIPGYGFYYLYQS 545
            |:|   |:...|...||.:.|.....::..:::|....: |:..::|:..::.||......::.:
Zfish   665 WRVCWAFVTPTILTFILALSLYQWKVMTYEDYTYPNWSM-VLGWLMVICSVIWIPIMFAIKMHLA 728

  Fly   546 TGTFCERFKRTCRP-TDWYPVEMEHR-QQYEEAVD 578
            .|:..||.|..|.| .||.|..|:|| ::|:..:|
Zfish   729 PGSLIERLKLVCSPQPDWGPFLMKHRGERYKNMID 763

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13795	NP_609138.3	SLC5-6-like_sbd	27..505	CDD:271356	129/536 (24%)
slc6a5	NP_001009557.1	SLC5-6-like_sbd	177..775	CDD:444915	151/620 (24%)