Protein Alignment CG13795 and SerT

DIOPT Version :10

• Sequence 1: NP_609138.3
• Gene: CG13795 / 34049
• FlyBaseID: FBgn0031937
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Alignment Length: 596
• Identity: 144/596 - (24%)
• Similarity: 264/596 - (44%)
• Gaps: 87/596 - (14%)

  Fly    13 PFSPDL--------------NRGKWDKPTDFMFACFGLALKLDVFVASFWMF-----FDMGILGI 58
            |.:|.|              .|..|.:..:|:.|..|.|:.|    .:.|.|     .:.|...:
  Fly    53 PLAPKLANNERILVVSVTERTRETWGQKAEFLLAVIGFAVDL----GNVWRFPYICYQNGGGAFL 113

  Fly    59 LPYFVYMSIYLVPIMVIHSFMGQFSSSGFISAF-RLSPFFKGMGYVSGFLTISMLIYYSIFAAVP 122
            :||.:::....:|:..:...:|||...|.:|.: |:.|..||:||....:.|.|.:||:......
  Fly   114 VPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWA 178

  Fly   123 LLFIINSFRPTLPW-SCEGLSSWHNGSATLSSSCNKTLILEDFSEYNRSHQLLHVPSVLYFQNHY 186
            :.::..||...||| ||:  :.|:..:....:|       |:|:|...|      |:..:|:.
  Fly   179 VYYLFASFTSKLPWTSCD--NPWNTENCMQVTS-------ENFTELATS------PAKEFFER-- 226

  Fly   187 DSMQQDAVPDWYKDYELSWHFVG---------LFAIIWVVIAFIFYKFSETAKFGKLIRYMVIVT 242
                  .|.:.||...|.  |:|         :|. ::|::.|..:|...:|  ||::....:..
  Fly   227 ------KVLESYKGNGLD--FMGPVKPTLALCVFG-VFVLVYFSLWKGVRSA--GKVVWVTALAP 280

  Fly   243 LVLLLVCFVRFLFLPGALNGLHRYVTP-----KASDMAMGVVSTFIMVLHAFGAGWGSVITLSSF 302
            .|:|::..||.:.||||..|:..|:||     |.|.:.:...|   .:..:.|.|:|:::.|||:
  Fly   281 YVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAAS---QIFFSLGPGFGTLLALSSY 342

  Fly   303 NGFKTDIMSYSWIISFGQIFIYIMFGMVSFMLEHY--FNELSDVDDNGHVLSHWLLYLSSASALS 365
            |.|..:....:.|.|........:.|.|.|.:..|  :.:.:.:|..| :....|:::....|::
  Fly   343 NKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKVG-LEGPGLVFIVYPEAIA 406

  Fly   366 TMAWPNLWTFIYYSMLLIAALIVMTTQIFTVLQSLFDEF-EVLRVRKQEVTFGLIGGIALCSFYF 429
            ||:....|:.|::.||:...|......:..::.:|.||: .|:..|::.....|:..|.||:...
  Fly   407 TMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRELFVLLLLAFIFLCALPT 471

  Fly   430 CTNHGIIFFSALGLDAIFSHSLLHLLLLLV----VLWIYGRERFQRDIEFMLG-QPFASWKVFIL 489
            .|..|::..:.|.   ::...|..|.::.|    |.|.||.:||..|:|.||| :|...|:: ..
  Fly   472 MTYGGVVLVNFLN---VYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRI-CW 532

  Fly   490 RFIAPIILV---ICLLAGIALSISEHSYSTTVVFVMSIVLVVLPILAIPGYGFY-YLYQSTGTFC 550
            .:|:|:.|:   |..:.|....:.|..|.....:.:...:....:|.||.|..| :.:.|.|...
  Fly   533 TYISPVFLLTIFIFSIMGYKEMLGEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFASKGGCR 597

  Fly   551 ERFKRTCRPTD 561
            :|.:.:.:|.|
  Fly   598 QRLQESFQPED 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13795	NP_609138.3	SLC5-6-like_sbd	27..505	CDD:271356	126/509 (25%)
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	139/572 (24%)