Protein Alignment CG13795 and Slc6a5

DIOPT Version :10

• Sequence 1: NP_609138.3
• Gene: CG13795 / 34049
• FlyBaseID: FBgn0031937
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: XP_006540608.1
• Gene: Slc6a5 / 104245
• MGIID: 105090
• Length: 831
• Species: Mus musculus
• Alignment Length: 614
• Identity: 154/614 - (25%)
• Similarity: 270/614 - (43%)
• Gaps: 84/614 - (13%)

  Fly    20 RGKWDKPTDFMFACFGLALKL-DVFVASFWMFFDMGILGILPYFVYMSIYLVPIMVIHSFMGQFS 83
            ||.|....||:.:..|.|:.| :|:...:..|.:.|...::||.:.:::..:||..:...:|||:
Mouse   225 RGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFA 289

  Fly    84 SSGFISAFRLSPFFKGMGYVSGFLTISMLIYYSIFAAVPLLFIINSFRPTLPW-SCEGLSSWHNG 147
            |.|.:|.::..|..:|.|.....:::.:.|||::.....|.::..||...||| ||.  :.|:
Mouse   290 SQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCN--NPWN-- 350

  Fly   148 SATLSSSC-NKTLILEDFSEYNRSHQLLHVPSVLYFQNHYDSMQQ------------DAVPDWYK 199
                :..| :||.:|.| |.....|..:.:.:..:....|.::..            ....:::|
Mouse   351 ----TPECKDKTKLLLD-SCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQTNKTFVSGSEEYFK 410

  Fly   200 DY------------ELSWHFVGLFAIIWVVIAFIFYKFSETAK----FGKLIRYMVIVTLVLLLV 248
            .:            |:.|.......:.||::      ::..||    .||::.:......|:|::
Mouse   411 YFVLKISAGIEYPGEIRWPLAFCLFLAWVIV------YASLAKGIKSSGKVVYFTATFPYVVLVI 469

  Fly   249 CFVRFLFLPGALNGLHRYVTPKASDMAMGVV--STFIMVLHAFGAGWGSVITLSSFNGFKTDIMS 311
            ..:|.:.||||..|:..::|||...:....|  .....:..:..|.||.:|||||:|.|..:...
Mouse   470 LLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYR 534

  Fly   312 YSWII----SFGQIFI-YIMFGMVSFMLEHYFNELSDVDDNGHVLSHWLLYLSSASALSTMAWPN 371
            .:.|:    |...||. :::|.::.||.......:.:|.|.|..:: :::|   ..||:.:....
Mouse   535 DTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIA-FVVY---PEALTRLPLSP 595

  Fly   372 LWTFIYYSMLLIAALIVMTTQIFTVLQSLFDEF-EVLRVRKQEVTFGLIGGIALCSFYFCTNHGI 435
            .|..|::.|||...|..|...|.|::.|:.||| :.||..|...|.|......:..|...|..||
Mouse   596 FWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGI 660

  Fly   436 IFFS---------ALGLDAIFSHSLLHLLLLLVVLWIYGRERFQRDIEFMLG-QPFASWKVFILR 490
            ..|.         ||.:.|||.        |:.:.::||.:||..|||.|:| :|...||| ...
Mouse   661 YMFQLVDTYAASYALVIIAIFE--------LVGISYVYGLQRFCEDIEMMIGFKPNIFWKV-CWA 716

  Fly   491 FIAPIILVICLLAGI----ALSISEHSYSTTVVFVMSIVLVVLPILAIPGYGFYYLYQSTGTFCE 551
            |:.|.||...|....    .::...:.|....: |:..:::...::.||......:|.:.|.|.|
Mouse   717 FVTPTILTFILCFSFYQWEPMTYGSYRYPNWSM-VLGWLMLACSVIWIPIMFVIKMYLAPGRFIE 780

  Fly   552 RFKRTCRP-TDWYPVEMEHR-QQYEEAVD 578
            |.|..|.| .||.|...:|| ::|:..:|
Mouse   781 RLKLVCSPQPDWGPFLAQHRGERYKNMID 809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13795	NP_609138.3	SLC5-6-like_sbd	27..505	CDD:271356	132/526 (25%)
Slc6a5	XP_006540608.1	SLC6sbd_GlyT2	225..821	CDD:271389	154/614 (25%)