Protein Alignment ZDHHC21 and app

DIOPT Version :10

• Sequence 1: NP_848661.1
• Gene: ZDHHC21 / 340481
• HGNCID: 20750
• Length: 265
• Species: Homo sapiens
• Sequence 2: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Alignment Length: 282
• Identity: 73/282 - (25%)
• Similarity: 113/282 - (40%)
• Gaps: 79/282 - (28%)

Human    16 CMGLI-------VFVWLYNIVLIPKIVLF-----PHYEEGHIPGILII--IFYGISIFCLVALVR 66
            |.||:       || :|..|::.....||     |...:...|.|.|:  :.|   .|.:.:|:|
  Fly    33 CDGLLMSAPHTGVF-YLTCILITGTSALFFAFDCPFLADSINPAIPIVGAVLY---FFTMSSLLR 93

Human    67 ASITDPGRLP-----------ENPKIPH-------------------GEREFWELCNKCNLMRPK 101
            .:.||||.:|           :..::|:                   |:....:.|..|.:.||.
  Fly    94 TTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFTCKIFRPP 158

Human   102 RSHHCSRCGHCVRRMDHHCPWINNCVGEDNHWLFLQLCFYTELLTCYALMFSFCHYYYFLPLKKR 166
            |:.|||.|.:||.|.||||||:.||||:.|:..|  ..|...|......:|| |...:.:.|.|:
  Fly   159 RASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFF--YLFLVSLAFLAVFIFS-CSVTHLVLLMKK 220

Human   167 NLDLF-VFRHE--LAIMRLAAFMGITMLVGITGLFYTQLIGIITDTTSIEKMS------------ 216
            ..::| |.:..  ..|:....|..|..::|:.| |:|.|  ..:|.|:.|.:.
  Fly   221 EHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAG-FHTYL--TTSDQTTNEDLKGSFSSKGGPRTQ 282

Human   217 ----------NCCEDISRPRKP 228
                      |||..:..|..|
  Fly   283 NPYSRGNICLNCCHILCGPMTP 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZDHHC21	NP_848661.1	DHHC	92..217	CDD:396215	44/149 (30%)
app	NP_648561.2	DHHC	146..270	CDD:396215	44/129 (34%)