Protein Alignment CG13794 and SLC6A12

DIOPT Version :10

• Sequence 1: NP_609137.2
• Gene: CG13794 / 34048
• FlyBaseID: FBgn0031936
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: NP_003035.3
• Gene: SLC6A12 / 6539
• HGNCID: 11045
• Length: 614
• Species: Homo sapiens
• Alignment Length: 601
• Identity: 140/601 - (23%)
• Similarity: 255/601 - (42%)
• Gaps: 98/601 - (16%)

  Fly    20 RGKWDKPTDYIFACFGLALKL-DIFVASYWFFFDMGIFGMLPYLVYMVIYLVPIMVIHSFMGQFS 83
            ||:|....:::.:..|..:.| :::...|..:.:.|....:||.::..:..:|:..:...:||::
Human    36 RGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYT 100

  Fly    84 SSGFISAFR-LSPFFKGMGYVSVFLTISMLIYYSIFAAVPLLFMINSFRPTLPWSCEGFKSWYNE 147
            |.|.::|:| :.|.|:|:|..||.:...:.:||.|..|..|.::.:||...|||
Human   101 SQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSELPW----------- 154

  Fly   148 SDGKMTTCNMTISEDLTDNSDNNTDFHRPHFHVPSVLYFLKHFESVQEENY--------SDLRQD 204
                 ||||...      |:::.|||.. |....:|..| ::|.|...|.:        |.:...
Human   155 -----TTCNNFW------NTEHCTDFLN-HSGAGTVTPF-ENFTSPVMEFWERRVLGITSGIHDL 206

  Fly   205 YDLSWRFVSLFVLVWAMVAFIFYKFSETAMFGKFIRYMVIGTLILLLVCFGRFLFLPGALLGLRK 269
            ..|.|......:|.|.:..|..:|..::.  ||.:.:......::|::...|.:.||||..|:..
Human   207 GSLRWELALCLLLAWVICYFCIWKGVKST--GKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIY 269

  Fly   270 YVTP-----SPDEIAMGIGSTFVMVLHAFGAGWGSVIALSSFNGFKT----DIMSYSWIISFGQI 325
            |:.|     ...::.|..|:   .:..:|....|.:.||.|:|.:..    |.::..::.| ...
Human   270 YLKPDLFRLKDPQVWMDAGT---QIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNS-ATS 330

  Fly   326 FI--FTMFGLVSYMLDHYYNEGIEGSFDKQVLTHWALYLSSATALSSLGWP---------NLWTF 379
            |:  |.:|.::.:|..   .:|:..|   :|       ..|...|:.:.:|         .||:.
Human   331 FVAGFVVFSILGFMSQ---EQGVPIS---EV-------AESGPGLAFIAFPKAVTMMPLSQLWSC 382

  Fly   380 IYYTMLLMAAL---IVITTQIFTVLQSLFDEFEVLRVRKQEVTFGLIGGIAVCSF----YFCTNH 437
            :::.||:...|   .|....:.|....:|..    ::||......||..|||..:    :..|..
Human   383 LFFIMLIFLGLDSQFVCVECLVTASIDMFPR----QLRKSGRRELLILTIAVMCYLIGLFLVTEG 443

  Fly   438 GITFFSALALDAIFSHSLLHLLLLLVVL--WIYGRERFQRDIEFMLG-QPFASWKVYILRFIAPI 499
            |:..|......|.....||.|.|..||.  |:||.:||..:||.|:| :|:...|:..| |:.|
Human   444 GMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWL-FLTP- 506

  Fly   500 ILIICLVVGI--LVCYMEHIYSSAIVL---GMSI--ILVILPILAIPGYGIYYIYRSTGSFCERF 557
              .:||...:  |..|....|::..|.   |.||  .|.:..::.:|.:.:..:.::.|.|.:|.
Human   507 --GLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRL 569

  Fly   558 KRTCRPTDWYPVEMEH 573
            ::...|....|...:|
Human   570 RQLITPDSSLPQPKQH 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13794	NP_609137.2	SLC5-6-like_sbd	27..509	CDD:271356	122/521 (23%)
SLC6A12	NP_003035.3	SLC6sbd_BGT1	35..575	CDD:212080	137/589 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	576..614		2/10 (20%)