Protein Alignment CG13794 and Slc6a2

DIOPT Version :10

• Sequence 1: NP_609137.2
• Gene: CG13794 / 34048
• FlyBaseID: FBgn0031936
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: NP_033235.3
• Gene: Slc6a2 / 20538
• MGIID: 1270850
• Length: 617
• Species: Mus musculus
• Alignment Length: 622
• Identity: 156/622 - (25%)
• Similarity: 277/622 - (44%)
• Gaps: 100/622 - (16%)

  Fly     6 SYDSGHKPFSPDLKRGKWDKPTDYIFACFGLALKLDIFVASYWFFFDM------GIFGMLPYLVY 64
            |.||..:|      |..|.|..|::.:..|.|:.|    |:.|.|..:      |.| ::||.::
Mouse    48 SQDSDAQP------RETWGKKIDFLLSVVGFAVDL----ANVWRFPYLCYKNGGGAF-LIPYTLF 101

  Fly    65 MVIYLVPIMVIHSFMGQFSSSGFISAFRLSPFFKGMGYVSVFLTISMLIYYSIFAAVPLLFMINS 129
            ::|..:|:..:...:||::..|..:.:::.|||||:||..:.:.:.:..||::..|..|.::..|
Mouse   102 LIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFAS 166

  Fly   130 FRPTLPWSCEGFKSWY--NESDGKMTTCNMTISEDLTDNSDNN----TDFHRP---HFHVPSVLY 185
            |...|||:..| .||.  |.:|.|:  .|.::..|.|..|...    .:|:..   |.|..|.::
Mouse   167 FTLNLPWTNCG-HSWNSPNCTDPKL--LNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIH 228

  Fly   186 FLKHFESVQEENYSDLRQDYDL-SWRFVSLFVLVWAMVAFIFYKFSETAMFGKFIRYMVIGTL-- 247
                              |..| .|:.:...::|..::.|..:|..:|:  ||.:  .:..||
Mouse   229 ------------------DIGLPQWQLLLCLMVVIVVLYFSLWKGVKTS--GKVV--WITATLPY 271

  Fly   248 ILLLVCFGRFLFLPGALLGLRKYVTPS---PDEIAMGIGSTFVMVLHAFGAGWGSVIALSSFNGF 309
            .:|.|.....:.||||..|:..|:...   ..|..:.|.:. ..:..:.|||:|.:||.:|:|.|
Mouse   272 FVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAA-TQIFFSLGAGFGVLIAFASYNKF 335

  Fly   310 KTD-------IMSYSWIISFGQIFIFTMFGLVSYMLDHYYNEGIEGSFDKQVLTHWA--LYLSSA 365
            ..:       ..:.:.:.||  |..|.:|.::.||. |.:...||     .|.|..|  :::...
Mouse   336 DNNCYRDALLTSTINCVTSF--ISGFAIFSILGYMA-HEHKVNIE-----DVATEGAGLVFILYP 392

  Fly   366 TALSSLGWPNLWTFIYYTMLLMAALIVITTQIFTVLQSLFDEFEVLRVRKQEVTFGLIGGIAVCS 430
            .|:|:|.....|..:::.|||...|......:..|:..|.|:|:||:..::..|..:.....:.:
Mouse   393 EAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCVVTISTFLLA 457

  Fly   431 FYFCTNHGITFFSALALDAIFSHSLLHLLLLLV-VLWIYGRERFQRDIEFMLG-QPFASWKVYIL 493
            .:..|..||...:.|...|..:..|..:|:..: |.|.||.:||..||:.|:| :|...|:: ..
Mouse   458 LFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRL-CW 521

  Fly   494 RFIAPIILIICLVVGIL----VCYMEHIY---SSAIVLGMSIILVILPILAIPGYGIYYIYRSTG 551
            :|::|..|:..:||.|:    :.|.::.|   ::.:..|:::..:||    :|.|.||......|
Mouse   522 KFVSPAFLLFVVVVSIINFKPLTYDDYTYPPWANWVGWGIALSSMIL----VPAYVIYKFLSIRG 582

  Fly   552 SFCERFKRTCRPTDWYPVEMEHRQQYEEAVSNTDMTQ 588
            |..||......|      |.||     ..|:..|:.|
Mouse   583 SLWERVAYGITP------ENEH-----HLVAQRDVRQ 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13794	NP_609137.2	SLC5-6-like_sbd	27..509	CDD:271356	128/513 (25%)
Slc6a2	NP_033235.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SLC5-6-like_sbd	56..615	CDD:444915	152/608 (25%)