Protein Alignment CG13793 and slc6a3

DIOPT Version :9

• Sequence 1: NP_609136.2
• Gene: CG13793 / 34047
• FlyBaseID: FBgn0031935
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_571830.1
• Gene: slc6a3 / 80787
• ZFINID: ZDB-GENE-010316-1
• Length: 629
• Species: Danio rerio
• Alignment Length: 594
• Identity: 153/594 - (25%)
• Similarity: 266/594 - (44%)
• Gaps: 94/594 - (15%)

  Fly    12 RGNWEKPTDYIFACFGLALKLDIFVASFWFF-----FNTGIFGMVPYLMYMVIYLVPIMVIHSYM 71
            |..|.|..|::.:..|.|:.|    |:.|.|     .|.|...:||||::|||..:|:..:...:
Zfish    76 RETWGKKIDFLLSVIGFAVDL----ANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELAL 136

  Fly    72 GQFSSSGFISAFRLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPW-SCEGFKS 135
            ||::..|....:::.|:|||:|:..:.:::.:..||.:..|..|.::.:||...||| .|.  .:
Zfish   137 GQYNREGAAGVWKICPIFKGVGFTVILISLYVGSYYNVIIAWALFYLFSSFSGELPWIHCN--NT 199

  Fly   136 WQNDTIAKWSICNATIAEEVAKETENDTYFYITNIHVPSVLYFKSHFESFQNDSELNDYEI-SWH 199
            |.:...   |..|||:.        ||||     ...|::.||:.........|.::|... .|.
Zfish   200 WNSPNC---SDPNATLL--------NDTY-----KTTPALEYFERGVLHVHESSGIDDLGAPRWQ 248

  Fly   200 LSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFLPGAHLGLKNYMTPSI 264
            |:...|:|...:.|..:|..:.:  ||.:.........:|.|..:|.:.||||..|:|.|:  |:
Zfish   249 LTACLAVVIVVLYFSLWKGVKTS--GKVVWITATMPYVVLTVLLLRGVTLPGAIDGIKAYL--SV 309

  Fly   265 EEFVVGTSSTFIMALQ----AFGAGWGSVITLSSFNGFKTN-----IMSYSWIISFGQIFI-YIM 319
            :...:..:..:|.|..    :.|.|:|.:|..||:|.|..|     |::.| |.|....|. :::
Zfish   310 DFLRLYDAQVWIEAATQICFSLGVGFGVLIAFSSYNKFSNNCYRDAIITSS-INSLTSFFSGFVI 373

  Fly   320 FGMVSFMLEHYFLGLPKPLFETQVINHWVLFLSSASALSSLGWPNLWTFIYYTMLLMAALIVITT 384
            |..:.:|.:.:.:.|.|...:    ...::|:....|:::|...::|..|::.|||...:.....
Zfish   374 FSFLGYMSQKHNVALDKVATD----GPGLVFIIYPEAIATLPGSSVWAVIFFIMLLTLGIDSAMG 434

  Fly   385 QIFTILQSLFDEFEQLRAKKQEVTLGLIGGLAVCSLYFCTNHGVLYFAILSIDAIFSQTLLHLLL 449
            .:.:::..|.|||:.|...::..||.::....:.||...||.|:..|.:|...|..:..|..:|:
Zfish   435 GMESVITGLIDEFKFLHKHRELFTLFIVVSTFLISLICVTNGGIYVFTLLDHFAAGTSILFGVLI 499

  Fly   450 LLV-VLWVYGRDRFQKDIKFMLGQ-PFASWKVFILRFVAPPTLVICLVLE--------------- 497
            ..: :.|.||.|||..||:.|:|| |...|:: ..:||:|..|:..:|:.
Zfish   500 EAIGIAWFYGVDRFSDDIEEMIGQRPGLYWRL-CWKFVSPCFLLFMVVVSFATFNPPKYGSYYFP 563

  Fly   498 -----IKMCLEEHSYSSSVLHFMAIILVGLPILAIPAYGFYYIHQRPGSISE-----LFRATDWY 552
                 :..||   |.||.::              :|.|.||.....|||..:     :...||.:
Zfish   564 TWATMVGWCL---SISSMIM--------------VPLYAFYKFCSLPGSFCDKLAYAITPETDHH 611

  Fly   553 PVEM-EYRQ 560
            .||. |.||
Zfish   612 LVERGEVRQ 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	131/517 (25%)
slc6a3	NP_571830.1	SLC6sbd_DAT1	76..623	CDD:212083	153/594 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810