DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13793 and Slc6a19

DIOPT Version :9

Sequence 1:	NP_609136.2	Gene:	CG13793 / 34047	FlyBaseID:	FBgn0031935	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001034811.2	Gene:	Slc6a19 / 664630	RGDID:	1594328	Length:	634	Species:	Rattus norvegicus

Alignment Length:	622	Identity:	140/622 - (22%)
Similarity:	243/622 - (39%)	Gaps:	148/622 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 NRGNWEKPTDYIFACFGLALKLDIFVASFWFF------FNTGIFGMVPYLMYMVIYLVPIMVIHS 69
            :|..|:....|:..|.|..:.|    .:.|.|      ...|.| |:|:|:.:|:..:|::.:..
  Rat    31 SRPKWDNKAQYMLTCVGFCVGL----GNVWRFPYLCQSHGGGAF-MIPFLILLVLEGIPLLHLEF 90

  Fly    70 YMGQFSSSGFISAF-RLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPWS-CEG 132
            .:||....|.:..: .:.|..||:|..|:|::..:.:||....|..:.:..|||:..|||| |
  Rat    91 AIGQRLRKGSVGVWSSIHPALKGVGIASMFVSFMVGLYYNTIIAWVMWYFFNSFQEPLPWSEC-- 153

  Fly   133 FKSWQNDTIAKWSICNATIAEEVAKETENDTYFYITNIHVPSVLYFKSHFESFQNDSELNDYEIS 197
             ...||.|         ...||.||.:..|.::|...:::.:.:          :||.    .|.
  Rat   154 -PLNQNQT---------GYVEECAKSSSVDYFWYRETLNISTSI----------SDSG----SIQ 194

  Fly   198 WHLSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFLPGAHLGLKNYMTP 262
            |.:.......|:.:.....:..|..  ||.:.........:|.:..:|.|.|.||..|:....||
  Rat   195 WWILLCLTCAWSVLYVCTIRGIETT--GKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTP 257

  Fly   263 SIEEFVVGTSSTFIMA----LQAFGAGWGSVITLSSFNGFKTNIMSYSWIISF--GQIFIY---I 318
            :|.|  :...:|::.|    ..:|...:|.:|:.||:|....|....|.|:|.  |...:|   :
  Rat   258 NITE--LSNPNTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNNCEMDSVIVSIINGFTSVYAATV 320

  Fly   319 MFGMVSFMLEHYF--------------LGLPK-----PLFETQVINHW----------------- 347
            ::.::.|.....|              ..||:     ..||  ...||
  Rat   321 VYSIIGFRATERFDDCVNTNILTLINGFDLPEGNVTAENFE--AYQHWCNATNPEAYAQLTFQTC 383

  Fly   348 --------------VLFLSSASALSSLGWPNLWTFIYYTMLLMAALIVITTQIFTILQSLFDEFE 398
                          :.|:....|::.:....||:.:::.||....           |.|:|...|
  Rat   384 DINTFLSEGVEGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLG-----------LSSMFGNME 437

  Fly   399 ---------QLRAKK--QEVTLGLIG-GLAVCSLYFCTNHGVLYFAIL-SIDAIFSQTLLHLLLL 450
                     .:..||  :|:..|||. |..:.:..|..|.|..:.::| |........::....:
  Rat   438 GVVVPLQDLNITPKKWPKELLTGLICLGTYLIAFIFTLNSGQYWLSLLDSYAGSIPLLIIAFCEM 502

  Fly   451 LVVLWVYGRDRFQKDIKFMLG-QPFASWKVFILRFVAPPTLVIC----LVLEIKMCL-------- 502
            ..|::|||.|||.|||:||:| :|...|:| ..|.|:|..:::.    .|:|:...|
  Rat   503 FAVVYVYGVDRFNKDIEFMIGHKPNIFWQV-TWRVVSPLIMLVIFLFFFVIEVNKQLMYSVWDPD 566

  Fly   503 -EEHSYSSSV-----LHFMAIILVGLPILAIPAYGFY 533
             ||...|..|     ::.:.:|:.|:|.|.||.:..|
  Rat   567 YEEFPKSQKVPYPDWVYAVVVIVAGVPCLTIPCFAIY 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	125/563 (22%)
Slc6a19	NP_001034811.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900