Protein Alignment CG13793 and SLC6A8

DIOPT Version :10

• Sequence 1: NP_609136.2
• Gene: CG13793 / 34047
• FlyBaseID: FBgn0031935
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_005620.1
• Gene: SLC6A8 / 6535
• HGNCID: 11055
• Length: 635
• Species: Homo sapiens
• Alignment Length: 605
• Identity: 138/605 - (22%)
• Similarity: 251/605 - (41%)
• Gaps: 102/605 - (16%)

  Fly    12 RGNWEKPTDYIFACFGLALKL-DIFVASFWFFFNTGIFGMVPYLMYMVIYLVPIMVIHSYMGQFS 75
            |..|.:..|:|.:|.|.|:.| :::...:..:.|.|...::||::..::..:||..:...:|||.
Human    52 RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFM 116

  Fly    76 SSGFISAFRLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPWSCEGFKSW---- 136
            .:|.|:.:.:.|||||:||.|:.:......||.:..|....:::.||..||||:..| .:|
Human   117 KAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCG-HTWNTPD 180

  Fly   137 -----QNDTIAKWSICNAT---IAEE---VAKETENDTYFYITNIHVPSVLYFKSHFESFQNDSE 190
                 :::..|..|:.|.|   :|:.   |.:..||........:.||..|
Human   181 CVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSGGLEVPGAL-------------- 231

  Fly   191 LNDYEISWHLSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFLPGAHLG 255
                  :|.::......|..:.|..:|..:..  ||.:.:.......:|:|..||.:.||||..|
Human   232 ------NWEVTLCLLACWVLVYFCVWKGVKST--GKIVYFTATFPYVVLVVLLVRGVLLPGALDG 288

  Fly   256 LKNYMTPSIEEFVVGTSSTFIMA----LQAFGAGWGSVITLSSFNGFKTNIMSYSWI---ISFGQ 313
            :..|:.|...:  :|:...:|.|    ..::..|.|::..|.|:|.|..|....:.|   |:.|.
Human   289 IIYYLKPDWSK--LGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGT 351

  Fly   314 IFI--YIMFGMVSFMLEHYFLGLPKPLFETQVINHWVLFLSSASALSSLGWPN---------LWT 367
            .|.  :::|.::.||.....:.:.|             ...|...|:.:.:|.         ||.
Human   352 SFFAGFVVFSILGFMAAEQGVHISK-------------VAESGPGLAFIAYPRAVTLMPVAPLWA 403

  Fly   368 FIYYTMLLMAALI--------VITTQIFTILQSLFDEFEQLRAKKQEVTLGLIGGLA-VCSLYFC 423
            .:::.|||:..|.        .||..:..:..|.:..|:      :|:::.|...|. |..|...
Human   404 ALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQ------REISVALCCALCFVIDLSMV 462

  Fly   424 TNHGVLYFAILSIDAIFSQTLLHLLL--LLVVLWVYGRDRFQKDIKFMLGQPFASWKVFILRFVA 486
            |:.|:..|.:....:....|||....  .:||.||||.|||..||..|:|.....|..:...|..
Human   463 TDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFT 527

  Fly   487 PPTLVICLVLEI--KMCLEEHSYSSSVLH-----FMAIILVGLPILAIPAYGFYYIHQRPGSISE 544
            |   ::|:.:.|  .:..|...|:::.::     .|........:|.:|.:....:.:..|:::|
Human   528 P---LVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAE 589

  Fly   545 LFRATD---WYPVEMEYRQQ 561
            .::...   |....:|||.|
Human   590 RWQHLTQPIWGLHHLEYRAQ 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	123/523 (24%)
SLC6A8	NP_005620.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28
		SLC6sbd_CT1	52..621	CDD:271397	138/605 (23%)