Protein Alignment CG13793 and SLC6A6

DIOPT Version :9

• Sequence 1: NP_609136.2
• Gene: CG13793 / 34047
• FlyBaseID: FBgn0031935
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001127839.2
• Gene: SLC6A6 / 6533
• HGNCID: 11052
• Length: 721
• Species: Homo sapiens
• Alignment Length: 521
• Identity: 121/521 - (23%)
• Similarity: 221/521 - (42%)
• Gaps: 71/521 - (13%)

  Fly    12 RGNWEKPTDYIFACFGLALKL-DIFVASFWFFFNTGIFGMVPYLMYMVIYLVPIMVIHSYMGQFS 75
            |..|....|::.:..|..:.| :::...:..:.|.|...::||.:::....:|:..:...:||::
Human   142 REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYT 206

  Fly    76 SSGFISAF-RLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPWS-CEGFKSW-- 136
            |.|.|:.: ::.|||.|:||.|:.:...|.:||.:..|....::..||:..|||: |.  .||
Human   207 SEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCN--HSWNT 269

  Fly   137 ---QNDTIAKWSICNATIAEEVAKETENDTYFYITNIHVPSVLYFKSHFESFQNDSELNDYEISW 198
               ..||:.|......||:.              ||...|.:.:::.:..|.....: :...:.|
Human   270 PHCMEDTMRKNKSVWITISS--------------TNFTSPVIEFWERNVLSLSPGID-HPGSLKW 319

  Fly   199 HLSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFLPGAHLGLKNYMTPS 263
            .|:....|||....|..:|.....  ||.:.:......|:|||..||.|.||||..|:|.|:.|.
Human   320 DLALCLLLVWLVCFFCIWKGVRST--GKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPD 382

  Fly   264 IEEFV-------VGTSSTFIMALQAFGAGWGSVITLSSFNGFKTNIMSYS-----WIISFGQIFI 316
            |....       .||...|..|:..     |::.:|.|:|.:|.|  ||.     ..::.|..|:
Human   383 ITRLEDPQVWIDAGTQIFFSYAICL-----GAMTSLGSYNKYKYN--SYRDCMLLGCLNSGTSFV 440

  Fly   317 --YIMFGMVSFMLEHYFLGLPKPLFETQVINHWVLFLSSASALSSLGWPNLWTFIYYTMLLMAAL 379
              :.:|.::.||.:...:.:.    :.......:.|::...|::.:..|..|:.:::.|||:..|
Human   441 SGFAIFSILGFMAQEQGVDIA----DVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGL 501

  Fly   380 ----IVITTQIFTILQSLFDEFEQLRAKKQEVTLGLIGGLAVCSLYF------CTNHGVLYFAIL 434
                :.:..|| |.|..|:..|.: :..::|:.:..     |||:.:      .|..|:..|.:.
Human   502 DSQFVEVEGQI-TSLVDLYPSFLR-KGYRREIFIAF-----VCSISYLLGLTMVTEGGMYVFQLF 559

  Fly   435 SIDAIFSQTLLHLLLL--LVVLWVYGRDRFQKDIKFMLGQPFASWKVFILRFVAPPTLVICLVLE 497
            ...|.....||.:...  .|:.|:||.|.....|:.|:|.....|..:....:.|...|.|.:..
Human   560 DYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFS 624

  Fly   498 I 498
            :
Human   625 L 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	119/512 (23%)
SLC6A6	NP_001127839.2	SLC6sbd_TauT	142..683	CDD:271398	121/521 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910