DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13793 and si:ch211-132b12.2

DIOPT Version :9

Sequence 1:	NP_609136.2	Gene:	CG13793 / 34047	FlyBaseID:	FBgn0031935	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001038688.1	Gene:	si:ch211-132b12.2 / 571877	ZFINID:	ZDB-GENE-050420-178	Length:	582	Species:	Danio rerio

Alignment Length:	574	Identity:	137/574 - (23%)
Similarity:	234/574 - (40%)	Gaps:	83/574 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RGNWEKPTDYIFACFGLALKL-DIFVASFWFFFNTGIFGMVPYLMYMVIYLVPIMVIHSYMGQFS 75
            ||||...|::|.|..|:.:.| :::...:..:.|.|...:||||:::|...||:.::.:.|||::
Zfish    11 RGNWGSKTEFILAVAGIVIGLGNVWRFPYLCYKNGGGAFLVPYLVFVVTCGVPLFLLETAMGQYT 75

  Fly    76 SSGFISAF-RLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPW-SCEGFKSWQN 138
            ..|.|:.: ||.||.:|:||....:.:...:||.|..|..|.::..||...||| ||:..  |..
Zfish    76 QEGGITCWHRLCPLAEGIGYAGQLIVLYSCMYYIIILAWALFYLAFSFSSQLPWASCDNI--WNT 138

  Fly   139 DTIAKWSICNATIAEEVAKETENDTYFYITNIHVPSVLYFKSHFESFQNDSEL-------NDYEI 196
            |.      | ..:||..            .|:..|.:|...|....|.....|       ...:|
Zfish   139 DA------C-VNLAENK------------LNLSTPMLLNSTSSVTEFWQHRVLALSGGIEKVGKI 184

  Fly   197 SWHLSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFLPGAHLGLKNYMT 261
            :|.:.....::|....|..:|..:..  ||.:.:.......:|||..:|.|.||||..|:..|:.
Zfish   185 NWEILLCLIVMWIICYFCVWKGVKST--GKVVYFTATFPYVMLLVLLIRGLTLPGALQGVVFYLY 247

  Fly   262 PSIEEFV-------VGTSSTFIMALQAFGAGWGSVITLSSFNGFKTNIMSYS-WII----SFGQI 314
            |......       .|....|..||     |..|:..|.|:|.:..|....| |:.    |...|
Zfish   248 PEPARLADPQVWMEAGAQIFFSYAL-----GTASLTVLGSYNKYNYNCYRSSLWLCLLNSSTSVI 307

  Fly   315 FIYIMFGMVSFMLEHYFLGLPKPLFETQVINHWVLFLSSASALSSLGWPNLWTFIYYTMLLMAAL 379
            ..:.:|.::.||.:...|    |:.|.......:.|::...|::.:.:|.||...::.|:::..|
Zfish   308 AGFAVFSVLGFMAQKQGL----PIEEVAESGPGLAFIAYPQAVAMMPFPQLWAACFFIMIILLGL 368

  Fly   380 IVITTQIFTILQSLFDEFEQL--RAKKQEVTLGLIGGLAVCSLYFC--------TNHGVLYFAIL 434
            ......:...:.|:.|.|..:  :|.::|:.|     |..|  .||        |..|:..|.:.
Zfish   369 DTQFVAMEVFMTSVIDLFPTVLRKAGRREIFL-----LLFC--LFCFFGQLVMVTEGGMYVFQLF 426

  Fly   435 SIDAIFSQTLLHLLLL--LVVLWVYGRDRFQKDIKFMLGQPFASWKVFILRFVAPPTLV---ICL 494
            ...|.....||.|.:.  |.:.||:|.::....|:.|.......|.:...:::.|...:   :|.
Zfish   427 DYYACSGACLLFLCVFESLAMGWVFGAEKMFGIIEDMTNSRPNYWFMLCWKYLTPIVSLASFVCS 491

  Fly   495 VLEIKMCLEEHSYSSSVLHFMAIILVGL----PILAIPAYGFYYIHQRPGSISE 544
            :::.|.......|   |....|.:|..|    .||.:|.:....:....|||.:
Zfish   492 LVKYKPLTFNRWY---VYPDWAYVLGWLLALSSILLVPGWALGRMFAGKGSIKQ 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	121/515 (23%)
si:ch211-132b12.2	NP_001038688.1	SLC6sbd-TauT-like	11..550	CDD:271387	137/574 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910