DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13793 and si:ch211-132b12.6

DIOPT Version :9

Sequence 1:	NP_609136.2	Gene:	CG13793 / 34047	FlyBaseID:	FBgn0031935	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001038523.1	Gene:	si:ch211-132b12.6 / 564583	ZFINID:	ZDB-GENE-050420-179	Length:	577	Species:	Danio rerio

Alignment Length:	502	Identity:	120/502 - (23%)
Similarity:	217/502 - (43%)	Gaps:	57/502 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RGNWEKPTDYIFACFGLALKL-DIFVASFWFFFNTGIFGMVPYLMYMVIYLVPIMVIHSYMGQFS 75
            ||.|.|..:::.|..|..:.| :::...:..:.|.|...::|||:::|...:|:.::.:.||||:
Zfish    11 RGFWGKKAEFLLAVAGNVVGLGNVWRFPYLCYRNGGGVFLIPYLVFVVTCGLPLFLLETAMGQFT 75

  Fly    76 SSGFISAF-RLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPW-SCEGFKSWQN 138
            ..|.|:.: ||.||.:|:||......:...:||||..|..|.::::||...||| ||...  |..
Zfish    76 HEGGITCWHRLCPLAQGVGYAGQLTVLYSCMYYTIILAWALFYLVSSFSSQLPWVSCNNI--WNT 138

  Fly   139 DTIAKWSICNATI-AEEVAKETENDTYFYITNIHVPSVLYFKSHFESFQNDSELNDYEISWHLSG 202
            |.....:..|.|. ...:|..|...|.|:...     ||......|...        :|:|.:..
Zfish   139 DNCVNLAAGNLTFNRTTLANSTSAATEFWERR-----VLSLSGGIEDIG--------KINWEILL 190

  Fly   203 LFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFLPGAHLGLKNYMTPSIEEF 267
            ....:|....|..:|..:..  ||.:.:.......:|||..:|.|.||||..|:..|:.|.....
Zfish   191 CLIAMWIICYFCIWKGVKST--GKVVYFTATFPYVMLLVLLIRGLTLPGALQGVVFYLYPEPARL 253

  Fly   268 V-------VGTSSTFIMALQAFGAGWGSVITLSSFNGFKTNIMSYS-W--IISFGQIFI--YIMF 320
            .       .||...|     ::....|.:|:|.|:|.:..|....| |  :::.|..|:  :.:|
Zfish   254 ADPQVWMEAGTQVFF-----SYSVCSGILISLGSYNQYSNNCYRDSFWLCLLNSGTSFVAGFAVF 313

  Fly   321 GMVSFMLEHYFLGLPKPLFETQVINHWVLFLSSASALSSLGWPNLWTFIYYTMLLMAALIVITTQ 385
            .::.||.  :..|:  |:.|.......:.|::...|::.:.:|.||...::.|:::..|......
Zfish   314 SVLGFMA--HVQGV--PVEEVAESGPGLAFIAYPQAMAMMPFPQLWAVCFFIMIILLGLDSQFVG 374

  Fly   386 IFTILQSLFDEFEQL--RAKKQEVTLGLIGGLAVC------SLYFCTNHGVLYFAILSIDAIFSQ 442
            |..::.|:.|.|.::  ||.::|:.:     |.:|      .|...|..|:..|.:....|....
Zfish   375 IECVITSVMDLFPEVLRRAGRRELFV-----LLLCLTCFFGQLIMVTEGGMYVFQLFDNYACNGA 434

  Fly   443 TLLHLLLL--LVVLWVYGRDRFQKDIKFMLGQPFASWKVFILRFVAP 487
            .||.|.:.  |.:.|::|.::....|:.|.......|.:...:::.|
Zfish   435 CLLFLSVFESLAIGWLFGAEKMFDIIEDMTESRPNYWFMLCWKYLTP 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	116/495 (23%)
si:ch211-132b12.6	NP_001038523.1	SLC6sbd-TauT-like	11..550	CDD:271387	120/502 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010