DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13793 and Gat

DIOPT Version :9

Sequence 1:	NP_609136.2	Gene:	CG13793 / 34047	FlyBaseID:	FBgn0031935	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_651930.2	Gene:	Gat / 43805	FlyBaseID:	FBgn0039915	Length:	636	Species:	Drosophila melanogaster

Alignment Length:	590	Identity:	153/590 - (25%)
Similarity:	271/590 - (45%)	Gaps:	87/590 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PDLNRGNWEKPTDYIFACFGLALKL-DIFVASFWFFFNTGIFGMVPYLMYMVIYLVPIMVIHSYM 71
            ||  ||:|....|:|.:..|||:.| :::...:..:.|.|...::||::.:.:..:|:..:...:
  Fly    56 PD--RGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFMELAL 118

  Fly    72 GQFSSSGFISAFRLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPW-SCEGF-- 133
            ||..:.|.:..|:::|:|||:||.:..::..:.:||.:..|..:.:...|.|..:|| :|..:
  Fly   119 GQMLTIGGLGVFKIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRADVPWRTCNNWWN 183

  Fly   134 -----KSWQNDTIAKW-SICNATIAEEVAKETENDTYFYITNIHVPSVLYFK------SH-FESF 185
                 ..::...:..| .|.|.|..:..:....|.|...:|:   |...:::      || .|..
  Fly   184 TVNCVSQYERKNLHCWDKIINGTTQKVCSVSALNITSLELTD---PVKEFWERRALQISHGIEEI 245

  Fly   186 QNDSELNDYEISWHLSGLFALVWATIAFIFYKFSEPAKF-GKCIRYMVIGTVALLLVCFVRFLFL 249
            .|        |.|.|:|...|||....|..:|   ..|: ||.:.:..:....||.:..||.:.|
  Fly   246 GN--------IRWELAGTLLLVWILCYFCIWK---GVKWTGKVVYFTALFPYVLLTILLVRGITL 299

  Fly   250 PGAHLGLKNYMTPSIEEFVVGTSSTFIMALQ----AFGAGWGSVITLSSFNGFKTNIMSYSWII- 309
            |||..|:|.|:.|:..:..  .|..:|.|:.    ::|.|.|:::.|.|:|.|..|:...:.|:
  Fly   300 PGALEGIKFYIIPNFSKLT--NSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVC 362

  Fly   310 ---SFGQIFI-YIMFGMVSFMLEHYFLGLPKPLFETQVINHWVLFLSSASALSSLGWPNLWTFIY 370
               |...:|. :::|.::.||....    .:|:.:.......:.||...||:..|....:|:.::
  Fly   363 TVNSSTSMFAGFVIFSVIGFMAHEQ----QRPVADVAASGPGLAFLVYPSAVLQLPGSPMWSCLF 423

  Fly   371 YTMLLMAALIVITTQIFTI---LQSLFDEFEQLRAKKQEVTLGLIGGLAVCSLYF-----CTNHG 427
            :.|||   ||.:.:|..|:   :.::.||:.||..|::|:.:.:     ||:|.:     |...|
  Fly   424 FFMLL---LIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAI-----VCALSYLVGLTCITQG 480

  Fly   428 VLY-FAILSIDAIFSQTLLHLLLL--LVVLWVYGRDRFQKDIKFMLG-QPFASWKVFILRFVAPP 488
            .:| |.||...|:....||.|:..  :.:.|.||.|||...||.|:| .|...|| |......|
  Fly   481 GMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTVWWK-FCWCVTTP- 543

  Fly   489 TLVICLVLEIKMCLE-------EHSY---SSSVLHFMAIILVGLPILAIPAYGFYYIHQRPGSIS 543
              .|||.:.....::       ::||   :.:...|.|:    ..:|.||.|.|:...:.||.:|
  Fly   544 --AICLGVFFFNIVQWTPVKYLDYSYPWWAHAFGWFTAL----SSMLYIPLYMFWLWKRTPGELS 602

  Fly   544 ELFRA 548
            |..||
  Fly   603 EKIRA 607

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	133/517 (26%)
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	151/586 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440720
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840