DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13793 and DAT

DIOPT Version :9

Sequence 1:	NP_609136.2	Gene:	CG13793 / 34047	FlyBaseID:	FBgn0031935	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001261026.1	Gene:	DAT / 36849	FlyBaseID:	FBgn0034136	Length:	644	Species:	Drosophila melanogaster

Alignment Length:	612	Identity:	153/612 - (25%)
Similarity:	269/612 - (43%)	Gaps:	94/612 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PFSPDLN-----RGNWEKPTDYIFACFGLALKLDIFVASFWFF-----FNTGIFGMVPYLMYMVI 59
            |...|.|     |..|....|::.:..|.|:.|    |:.|.|     .|.|...:|||.:.:|:
  Fly    15 PHDNDNNSISDERETWSGKVDFLLSVIGFAVDL----ANVWRFPYLCYKNGGGAFLVPYGIMLVV 75

  Fly    60 YLVPIMVIHSYMGQFSSSGFISAF-RLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFR 123
            ..:|:..:...:||.:..|.|:.: ||.|||||:||..:.:...:..||.:..|..|.|...||.
  Fly    76 GGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFT 140

  Fly   124 PTLPW-SCEGFKSWQNDTIAKWSICNATIAEEVAKETE-----------NDTYFYITNIHVPSVL 176
            .:||| ||...  |.......:...||:....:...::           |:||...:::...:|
  Fly   141 NSLPWTSCNNI--WNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAV- 202

  Fly   177 YFKSHFESFQNDS---------ELNDYE-------ISWHLSGLFALVWATIAFIFYKFSEPAKFG 225
               .|.|.||:.:         |||..|       |.|.::....:|:....|..:|....:  |
  Fly   203 ---GHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTS--G 262

  Fly   226 KCIRYMVIGTVALLLVCFVRFLFLPGAHLGLKNYMTPSI------EEFVVGTSSTFIMALQAFGA 284
            |.:.:..:...|:||:..:|.|.|||:.||::.|:||:.      |.:|...:..|.    :.|.
  Fly   263 KVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFF----SLGP 323

  Fly   285 GWGSVITLSSFNGFKTNIMSYSWIISF---GQIFI--YIMFGMVSFMLEHYFLGLPKPLFETQVI 344
            |:|.::..:|:|.:..|:...:.:.||   ...||  :::|.::.:|.  :.||:  .:.:....
  Fly   324 GFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMA--HTLGV--RIEDVATE 384

  Fly   345 NHWVLFLSSASALSSLGWPNLWTFIYYTMLLMAALIVITTQIFTILQSLFDEFEQLRAKKQEVTL 409
            ...::|:...:|::::.....|..|::.|||...|.........|:.:|.|||.:::..::....
  Fly   385 GPGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVA 449

  Fly   410 GLIGGLAVCSLYFCTNHGVLYFAILS--------IDAIFSQTLLHLLLLLVVLWVYGRDRFQKDI 466
            ||.....|..|..||..|..:|.:|.        :.|:|.:.       :.|.|:||.:||.:||
  Fly   450 GLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEA-------IAVSWIYGTNRFSEDI 507

  Fly   467 KFMLG-QPFASWKVFILRFVAPPTLVICLVLEIKMCLEEHSYSSSV----LHFMAIILVGLPILA 526
            :.|:| .|...|:| ..|||||..|:...|..: :..|..:|:..|    .:.:...:.|..::.
  Fly   508 RDMIGFPPGRYWQV-CWRFVAPIFLLFITVYGL-IGYEPLTYADYVYPSWANALGWCIAGSSVVM 570

  Fly   527 IPAYGFYYIHQRPGSISELFR--ATDW 551
            |||...:.:...|||:.:.|.  .|.|
  Fly   571 IPAVAIFKLLSTPGSLRQRFTILTTPW 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	135/532 (25%)
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	149/598 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440813
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840