DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13793 and CG13796

DIOPT Version :9

Sequence 1:	NP_609136.2	Gene:	CG13793 / 34047	FlyBaseID:	FBgn0031935	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001137807.1	Gene:	CG13796 / 34051	FlyBaseID:	FBgn0031939	Length:	641	Species:	Drosophila melanogaster

Alignment Length:	591	Identity:	183/591 - (30%)
Similarity:	297/591 - (50%)	Gaps:	58/591 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KPFSPDLNRGNWEKPTDYIFACFGLALKLDIF--VASFWFFFNTGIFGMVPYLMYMVIYLVPIMV 66
            :|:..|..||.|.|..|:.||....|....||  :::|.......:..::.|||.|:.|.:||.:
  Fly    76 RPYRHDKCRGRWAKSADFYFASCTHAFSSLIFSELSTFGILHGGWLLFIIAYLMGMLFYSLPIFL 140

  Fly    67 IHSYMGQFSSSGFISAFRLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPW-SC 130
            |.:::|||||||.|||||::|:|||:||..|.|.:..|.||:|.|.|||::.:||..|.:|| ||
  Fly   141 IQAFLGQFSSSGTISAFRVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMSC 205

  Fly   131 EGFKSWQNDTIAKWSICNATIAEEVAKETENDTYFYITNIHVPSVLYFKSHFESFQNDSELNDYE 195
            .  .||.              .:|.:.....|...|..:.| .:|.:|:|...|....|  ....
  Fly   206 N--NSWN--------------TQECSLHENYDVDDYRVDPH-STVEFFRSMIASTAKGS--TSMS 251

  Fly   196 ISWH-LSGLFALVWATIAFIFYKFSEPAKF-GKCIRYMVIGTVALLLVCFVRFLFLPGAHLG-LK 257
            |||. |.|:.: :|..:..:..|   |..| ||.:|...:......:..|:..|........ |.
  Fly   252 ISWSMLIGVLS-IWLVVLALLLK---PVAFIGKVLRCSCVLMFGFFVAVFLYLLIHEQVTFDTLH 312

  Fly   258 NYMTPSIEEF--VVGTSST-FIMALQAFGAGWGSVITLSSFNGFKTNIMSYS-WIISFGQIFIYI 318
            .|..|.::.|  ::.|:.| .:||..|.|.||||:|||||:|.|:.:....| |:     ...:|
  Fly   313 YYWMPQLDSFDSILATARTALLMAGGALGPGWGSIITLSSYNNFRRDAERLSIWV-----CLTHI 372

  Fly   319 MFGMVSFML-----EHY--FLGLPKPLFETQVINHWVLFLSSASALSSL-GWPNLWTFIYYTMLL 375
            ..|::..:.     :|:  .:|: .||...:..:...|:|..:...... ..||||.|:::.|:.
  Fly   373 TIGLMGLLCCNVAHDHFEDHVGM-MPLHVDEKHHMQFLYLCFSYLFGRFTTTPNLWAFLFFGMIF 436

  Fly   376 MAALIVITTQIFTILQSLFDEFEQLRAKKQEVTLGLIGGLAVCSLYFCTNHGVLYFAILSIDAIF 440
            ::.|..:..|:.:::.:||||||.||:::..|...|:..|...|:||||..|......|...|:|
  Fly   437 LSELCALIIQMMSVITALFDEFETLRSRRILVISSLVFCLTASSVYFCTQLGFSQLTQLPNLAVF 501

  Fly   441 SQTLLHLLLLLVVLWVYGRDRFQKDIKFMLGQPFASWKVFILRFVAPPTLVICLVLEIKMCLEEH 505
            :..|:..:|:|:..|||||.|||.|::||||:..:|:|:|.:||..|..|.:|| .::     .:
  Fly   502 THLLISGILVLMTTWVYGRVRFQCDLQFMLGKTISSFKIFFIRFATPIFLGLCL-FQL-----TY 560

  Fly   506 SYSSSVLHFMAI-ILVGLPILAIPAYGFYYIHQRPGS----ISELFRATDWYPVEMEYRQQYGEL 565
            .::...:|.:.| :..||.:|...:|..|.:.:..|.    :.:.....||:||:.:.|:.|.|:
  Fly   561 LFTRDRIHDVLIYVSQGLILLTAISYMVYKVCRTNGDWRQRLQQCLAPHDWHPVDADNRRFYEEI 625

  Fly   566 VQKSEM 571
            :..|||
  Fly   626 MGISEM 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	159/496 (32%)
CG13796	NP_001137807.1	SLC5-6-like_sbd	123..610	CDD:294310	160/521 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473192
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007612
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840