Protein Alignment CG13793 and SLC6A19

DIOPT Version :10

• Sequence 1: NP_609136.2
• Gene: CG13793 / 34047
• FlyBaseID: FBgn0031935
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001003841.1
• Gene: SLC6A19 / 340024
• HGNCID: 27960
• Length: 634
• Species: Homo sapiens
• Alignment Length: 641
• Identity: 144/641 - (22%)
• Similarity: 259/641 - (40%)
• Gaps: 146/641 - (22%)

  Fly    11 NRGNWEKPTDYIFACFGLALKLDIFVASFWFF------FNTGIFGMVPYLMYMVIYLVPIMVIHS 69
            :|..|:....|:..|.|..:.|    .:.|.|      ...|.| |:|:|:.:|:..:|::.:..
Human    31 SRPKWDNKAQYMLTCLGFCVGL----GNVWRFPYLCQSHGGGAF-MIPFLILLVLEGIPLLYLEF 90

  Fly    70 YMGQFSSSGFISAF-RLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPWS-CEG 132
            .:||....|.:..: .:.|..||:|..|:..:..:.:||....:..:.::.|||:..|||| |.
Human    91 AIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFNSFQEPLPWSDCP- 154

  Fly   133 FKSWQNDTIAKWSICNAT-IAEEVAKETENDTYFYITNIHVPSVLYFKSHFESFQNDSELNDYEI 196
                .|:        |.| ..:|.|:.:..|.::|...:::.:.:          :||.    .|
Human   155 ----LNE--------NQTGYVDECARSSPVDYFWYRETLNISTSI----------SDSG----SI 193

  Fly   197 SWHLSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFLPGAHLGLKNYMT 261
            .|.:....|..|:.:.....:..|..  ||.:.........:|.:..:|.|.|.||..|:....|
Human   194 QWWMLLCLACAWSVLYMCTIRGIETT--GKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFT 256

  Fly   262 PSIEEFVVGTSSTFIMA----LQAFGAGWGSVITLSSFNGFKTNIMSYSWIIS----FGQIFI-Y 317
            |::.|  :....|::.|    ..:|...:|.:|:.||:|....|....|.|:|    |..::: .
Human   257 PNVTE--LAQPDTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCEKDSVIVSIINGFTSVYVAI 319

  Fly   318 IMFGMVSFMLEHYF--------------LGLPKP-------------------------LFETQV 343
            :::.::.|.....:              ..||:.                         :|:|..
Human   320 VVYSVIGFRATQRYDDCFSTNILTLINGFDLPEGNVTQENFVDMQQRCNASDPAAYAQLVFQTCD 384

  Fly   344 INHWVLFLSSA------------SALSSLGWPNLWTFIYYTMLLMAALIVITTQIFTILQSLFDE 396
            ||   .|||.|            .|::.:....||:.:::.||....|    :.:|..::.:...
Human   385 IN---AFLSEAVEGTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCLGL----SSMFGNMEGVVVP 442

  Fly   397 FEQLRA----KKQEVTLGLIG-GLAVCSLYFCTNHGVLYFAIL-SIDAIFSQTLLHLLLLLVVLW 455
            .:.||.    ..:||..|||. |..:....|..|.|..:.::| |........::....:..|::
Human   443 LQDLRVIPPKWPKEVLTGLICLGTFLIGFIFTLNSGQYWLSLLDSYAGSIPLLIIAFCEMFSVVY 507

  Fly   456 VYGRDRFQKDIKFMLG-QPFASWKVFILRFVAPPTLVIC----LVLEIKMCL---------EEHS 506
            |||.|||.|||:||:| :|...|:| ..|.|:|..::|.    .|:|:...|         ||..
Human   508 VYGVDRFNKDIEFMIGHKPNIFWQV-TWRVVSPLLMLIIFLFFFVVEVSQELTYSIWDPGYEEFP 571

  Fly   507 YSSSV-----LHFMAIILVGLPILAIPAYGFYYI---H-QRPGS----ISELFRAT 549
            .|..:     ::.:.:|:.|:|.|.||.|..|.:   | |:||.    :|.|..|:
Human   572 KSQKISYPNWVYVVVVIVAGVPSLTIPGYAIYKLIRNHCQKPGDHQGLVSTLSTAS 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	122/558 (22%)
SLC6A19	NP_001003841.1	SLC5-6-like_sbd	32..612	CDD:444915	138/623 (22%)