DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13793 and Slc6a14

DIOPT Version :9

Sequence 1:	NP_609136.2	Gene:	CG13793 / 34047	FlyBaseID:	FBgn0031935	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	XP_038955501.1	Gene:	Slc6a14 / 298340	RGDID:	1561810	Length:	646	Species:	Rattus norvegicus

Alignment Length:	644	Identity:	152/644 - (23%)
Similarity:	277/644 - (43%)	Gaps:	129/644 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RGNWEKPTDYIFACFGLALKL-DIFVASFWFFFNTGIFGMVPYLMYMVIYLVPIMVIHSYMGQFS 75
            ||||.|.:||:.:..|.|:.| :::...:..:.|.|...::||.:.:.:..:|:..:...:|||:
  Rat    42 RGNWSKKSDYLLSMVGYAVGLGNVWRFPYLTYTNGGGAFLIPYAIMLALAGLPLFFLECSLGQFA 106

  Fly    76 SSGFISAFRLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPW-SCEGFKSWQND 139
            |.|.:|.:|:.|||:|:|...:.::|.:.|||.:..|..|.::..||:..||| :|.  .||.:|
  Rat   107 SLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYLFASFQSVLPWANCS--SSWADD 169

  Fly   140 TIAKWSICNATIAEEVAKETENDTYFYITNIH-----------------VPSVLYFKSHFESFQN 187
            ..::..|....   .|:.:|..|.:..|:.::                 :||..|:..  .:.:.
  Rat   170 NCSRQPIVTGC---RVSTDTGGDMFMNISWVNSNNFTCLNGSEVFRPGQLPSEQYWDK--VTLRR 229

  Fly   188 DSELNDY-EISWHLSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFLPG 251
            .|.:::. .|.|:|:....|.|..:....:|..:.:  ||.:.:..:....:||:..:|...|.|
  Rat   230 SSGMDETGVIVWYLALCLLLAWIIVGAALFKGIKSS--GKVVYFTALFPYVVLLILLIRGATLEG 292

  Fly   252 AHLGLKNYMTPSIEEFVVGTSSTFI----------MALQAF---GAGWGSVITLSSFNGFKTNIM 303
            |..|:..|         :|..|.|.          .|.|.|   ...||.::.|||:|.|..|..
  Rat   293 ASKGISYY---------IGAQSNFTKLREAEVWKDAATQIFYSLSVAWGGLVALSSYNKFNNNCY 348

  Fly   304 SYSWIISFGQIFIYIMFGMVSF-MLEHYFLGLPKPLFETQVINHWVLFLSSASALSSLGWPNLWT 367
            |.:.|:........:..|...| :|.|......|.:.:.......:.|::...||:.|.....|:
  Rat   349 SDAIIVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIAYPEALAQLPGGPFWS 413

  Fly   368 FIYYTMLL-------MAALIVITTQIFTILQSLFDEFEQLRAKKQEVTLG------LIGGLAVCS 419
            .:::.|||       .|::..|||.|    |.||.  :.::..:..:|||      |:|.:.|..
  Rat   414 ILFFFMLLTLGLDSQFASIETITTTI----QDLFP--KAMKRMRVPITLGCCLILFLLGLVCVTQ 472

  Fly   420 L---------YFCTNHGVLYFAILSIDAIFSQTLLHLLLLLVVLWVYGRDRFQKDIKFMLGQP-- 473
            .         :||...|:|..|||.|..|              :|:||.:||.:||:.|:|..
  Rat   473 AGIYWVHLIDHFCAGWGILIAAILEIAGI--------------IWIYGGNRFIEDIEMMIGAKRW 523

  Fly   474 ------FASWKVFILRFVAPPTLVICLVLEIKMCLEEHSYS-------SSVLHFMAII--LVGLP 523
                  .|.|      ||..|.|:..:::...:.....:|:       ...|.:..||  ::.:|
  Rat   524 LFWLWWRACW------FVITPILLSAILVWSLVKFHRPNYADIPYPDWGVALGWCMIIFCIIWIP 582

  Fly   524 ILAIPAYGFYYIHQRPGSISELF-----RATDWYPVEMEYR-QQYGELVQKSEMT-HQL 575
            |:||     ..|.:..|:|.:..     .|::|.|...::| ::|.::.:.::.| |::
  Rat   583 IMAI-----IKIVRAEGNILQRIIKCCRPASNWGPYLEKHRGERYKDMAEPAKETDHEI 636

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	129/542 (24%)
Slc6a14	XP_038955501.1	SLC6sbd_ATB0	42..645	CDD:271391	152/644 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810