Protein Alignment CG13793 and SLC6A16

DIOPT Version :10

• Sequence 1: NP_609136.2
• Gene: CG13793 / 34047
• FlyBaseID: FBgn0031935
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_047294657.1
• Gene: SLC6A16 / 28968
• HGNCID: 13622
• Length: 795
• Species: Homo sapiens
• Alignment Length: 678
• Identity: 152/678 - (22%)
• Similarity: 268/678 - (39%)
• Gaps: 164/678 - (24%)

  Fly     1 MASKPFSPDLNRGNWEKPTDYIFACFGLALKLDIFVASFWFFFNTG--IFGMVPYLMYMVIYLVP 63
            :.::||        |...|:||.|..|.::|........:.:.|:|  .|..: |:..:.:..||
Human   159 LLARPF--------WSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAI-YIFMLFLVGVP 214

  Fly    64 IMVIHSYMGQFSSSGFISAFR-LSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLP 127
            ::.:....||....|.:..:: ::|...|:||.|..:...|.:|:.:..:..:.::..||:..:|
Human   215 LLFLEMAAGQSMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSWIIFYMSQSFQFPVP 279

  Fly   128 WSCEGFKSWQNDTIAKWSICNATI-AEEVAKETENDTYFYITNIHVPSVLYFKSHFESFQNDSEL 191
                            |..|..|: :.....|.|..|         ||:.::  :.::.:....:
Human   280 ----------------WEKCPLTMNSSGFDPECERTT---------PSIYFW--YQQALKASDRI 317

  Fly   192 ND-----------YEISWHLSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVR 245
            .|           :.:.|.|.|.|.:            :.....||.|..:|:....:::..|:|
Human   318 EDGGSPVYSLVLPFFLCWCLVGAFMI------------NGLKSTGKVIYVLVLLPCFIIVGFFIR 370

  Fly   246 FLFLPGAHLGLKNYMTPSIEEFVVGTSSTFIMA----LQAFGAGWGSVITLSSFNGFKTNIMSYS 306
            .|.|.||..||:..:...|.:  |...|.:.:|    |...|.|.|||.:|:|:.....|.:|.:
Human   371 TLLLEGAKFGLQQLVVAKISD--VYNMSVWSLAGGQVLSNTGIGLGSVASLASYMPQSNNCLSDA 433

  Fly   307 WIISFGQIFIYIMFGMVSF---------------------MLEHYFLG-LP---KP----LFE-T 341
            :::|...:...::|...:|                     :|:...|| ||   ||    |:. |
Human   434 FLVSVINLLTLLVFTSFNFCVLGFWATVITHRCCERNAEILLKLINLGKLPPDAKPPVNLLYNPT 498

  Fly   342 QVINHWV---------------------------------LFLSSASALSSLGWPNLWTFIYYTM 373
            .:.|.|:                                 .|||...|:|.|.....|:||::.|
Human   499 SIYNAWLSGLPQHIKSMVLREVTECNIETQFLKASEGPKFAFLSFVEAMSFLPPSVFWSFIFFLM 563

  Fly   374 LL---MAALIVITTQIFTILQSLFDEFEQLRAKKQEVTLGLIGGLAVCSLYFCTNHGVLYFAILS 435
            ||   :::.|.|...|.|.||   |.|...|...:.:.:|:...:.||.|:|....|..:..:||
Human   564 LLAMGLSSAIGIMQGIITPLQ---DTFSFFRKHTKLLIVGVFLLMFVCGLFFTRPSGSYFIRLLS 625

  Fly   436 ID--AIFSQTLLHLLLLLVVLWVYGRDRFQKDIKFMLGQPFASWKVFILRFVAPPTLVICLV-LE 497
             |  .:|...::.:...:.|.|.||..||..|:..:||.|.:....::...:.|..|:|..| :.
Human   626 -DYWIVFPIIVVVVFETMAVSWAYGARRFLADLTILLGHPISPIFGWLWPHLCPVVLLIIFVTMM 689

  Fly   498 IKMCLEEHSY-------SSSVLH-------FMAIILVGLPILAIPAYGFYY--IHQ---RPGSIS 543
            :.:|::..:|       |..||.       .:.|.|..:.||.|||| |.|  ||:   ||.|..
Human   690 VHLCMKPITYMSWDSSTSKEVLRPYPPWALLLMITLFAIVILPIPAY-FVYCRIHRIPFRPKSGD 753

  Fly   544 ELFRATDWYPVEMEYRQQYGELVQKSEM 571
            ....|:...|  :.::....:.|||.|:
Human   754 GPMTASTSLP--LSHQLTPSKEVQKEEI 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	123/566 (22%)
SLC6A16	XP_047294657.1	SLC6sbd_NTT5	162..732	CDD:271392	134/623 (22%)