DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13793 and Slc6a6

DIOPT Version :9

Sequence 1:	NP_609136.2	Gene:	CG13793 / 34047	FlyBaseID:	FBgn0031935	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	XP_030111163.1	Gene:	Slc6a6 / 21366	MGIID:	98488	Length:	631	Species:	Mus musculus

Alignment Length:	517	Identity:	120/517 - (23%)
Similarity:	227/517 - (43%)	Gaps:	63/517 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RGNWEKPTDYIFACFGLALKL-DIFVASFWFFFNTGIFGMVPYLMYMVIYLVPIMVIHSYMGQFS 75
            |..|....|::.:..|..:.| :::...:..:.|.|...::||.:::....:|:..:...:||::
Mouse    51 REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEVIIGQYT 115

  Fly    76 SSGFISAF-RLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPWS-CEGFKSW-- 136
            |.|.|:.: ::.|||.|:||.|:.:...|.:||.:..|....::.:||:..|||: |.  .||
Mouse   116 SEGGITCWEKICPLFSGIGYASIVIVSLLNVYYIVILAWATYYLFHSFQKDLPWAHCN--HSWNT 178

  Fly   137 ---QNDTIAK----WSICNATIAEEVAKETENDTYFYITNIHVPSVLYFKSHFESFQNDSELNDY 194
               ..||:.:    |          |:..|.|.|        .|.:.:::.:..|..:..: |..
Mouse   179 PQCMEDTLRRNESHW----------VSLSTANFT--------SPVIEFWERNVLSLSSGID-NPG 224

  Fly   195 EISWHLSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFLPGAHLGLKNY 259
            .:.|.|:....|||....|..:|.....  ||.:.:......|:|||..||.|.||||..|:|.|
Mouse   225 SLKWDLALCLLLVWLVCFFCIWKGVRST--GKVVYFTATFPFAMLLVLLVRGLTLPGAGEGIKFY 287

  Fly   260 MTPSIEEFVVGTSSTFIMA----LQAFGAGWGSVITLSSFNGFKTNIMSYS-----WIISFGQIF 315
            :.|.|..  :|....:|.|    ..::....|::.:|.|:|.:|.|  ||.     ..::.|..|
Mouse   288 LYPDISR--LGDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYN--SYRDCMLLGCLNSGTSF 348

  Fly   316 I--YIMFGMVSFMLEHYFLGLPKPLFETQVINHWVLFLSSASALSSLGWPNLWTFIYYTMLLMAA 378
            :  :.:|.::.||.:...:.:.    :.......:.|::...|::.:..|..|:.:::.|||:..
Mouse   349 VSGFAIFSILGFMAQEQGVDIA----DVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLG 409

  Fly   379 L----IVITTQIFTILQSLFDEFEQLRAKKQEVTLGLIGGLA-VCSLYFCTNHGVLYFAILSIDA 438
            |    :.:..|| |.|..|:..|.: :..::|:.:.::..:: :..|...|..|:..|.:....|
Mouse   410 LDSQFVEVEGQI-TSLVDLYPSFLR-KGYRREIFIAILCSISYLLGLTMVTEGGMYVFQLFDYYA 472

  Fly   439 IFSQTLLHLLLL--LVVLWVYGRDRFQKDIKFMLGQPFASWKVFILRFVAPPTLVICLVLEI 498
            .....||.:...  .|:.|:||.|.....|:.|:|.....|..:....:.|...|.|.|..:
Mouse   473 ASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPALCVGCFVFSL 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	118/508 (23%)
Slc6a6	XP_030111163.1	SLC5-6-like_sbd	51..592	CDD:382020	120/517 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000