DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13793 and Slc6a13

DIOPT Version :9

Sequence 1:	NP_609136.2	Gene:	CG13793 / 34047	FlyBaseID:	FBgn0031935	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	XP_006237280.2	Gene:	Slc6a13 / 171163	RGDID:	620788	Length:	608	Species:	Rattus norvegicus

Alignment Length:	631	Identity:	132/631 - (20%)
Similarity:	251/631 - (39%)	Gaps:	122/631 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SKPFSP---------DLNRGNWEKPTDYIFACFGLALKL-DIFVASFWFFFNTGIFGMVPYLMYM 57
            :||..|         .|.|..|....:::.:..|..:.| :::...:..:.|.|....:|||:::
  Rat    14 TKPVCPVMEKVEEDGTLEREQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFL 78

  Fly    58 VIYLVPIMVIHSYMGQFSSSGFISAFR-LSPLFK------GMGYVSLFLTITLLIYYTIFAAVPL 115
            ....:|:..:.:.:||:::.|.|:|:| :.|:|:      |:||.|..:...|.:||.:..|..|
  Rat    79 FTCGIPVFFLETALGQYTNQGGITAWRKICPIFEASVPSPGIGYASQMIVSLLNVYYIVVLAWAL 143

  Fly   116 LFVLNSFRPTLPW-SCEGFKSWQNDTIAKWSICNATIAEEVAKETENDTYFYITNIHVPSVLYFK 179
            .::.:||...||| ||.  ..|..:...::            ::|.|.......|...|.:.:::
  Rat   144 FYLFSSFTTDLPWGSCS--HEWNTENCVEF------------QKTNNSLNVTSENATSPVIEFWE 194

  Fly   180 SHF----ESFQNDSELNDYEISWHLSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLL 240
            ...    :..|:...|.     |.|.....|.|....|..:|..:..  ||.:.:.......:|:
  Rat   195 RRVLKISDGIQHLGSLR-----WELVLCLLLAWIICYFCIWKGVKST--GKVVYFTATFPYLMLV 252

  Fly   241 VCFVRFLFLPGAHLGLKNYMTPSIEE-------FVVGTSSTFIMALQAFGAGWGSVITLSSFNGF 298
            |..:|.:.||||..|::.|:.|:|..       ...||...|     :|....|.:..|.|:|.:
  Rat   253 VLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFF-----SFAICLGCLTALGSYNKY 312

  Fly   299 KTNI-----------MSYSWIISFGQIFIYIMFGMVSFMLEHYFLGLPKPLFETQVINHWVLFLS 352
            ..|.           .|.|::..|.      :|.::.||.:...:    |:.|.......:.|::
  Rat   313 HNNCYRDCVALCILNSSTSFVAGFA------IFSILGFMSQEQGV----PISEVAESGPGLAFIA 367

  Fly   353 SASALSSLGWPNLWTFIYYTMLLMAALIVITTQIFTILQSLFDEFEQLRAKK--QEVTLGLIGGL 415
            ...|:..|.:..||...::.|:::..|......:.:::.:|.|.:.::..||  :|:.:.::..:
  Rat   368 YPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREILILIVSVV 432

  Fly   416 A-VCSLYFCTNHGVLYFAILSIDAIFSQTLLHLLLL--LVVLWVYGRDRFQKDIKFMLGQPFASW 477
            : ...|...|..|:..|.:....|.....||.:.:.  |.|.||||..||..:|:.|:|  :..|
  Rat   433 SFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGASRFYDNIEDMIG--YKPW 495

  Fly   478 KVFILRFVAPPTLVIC-LVLEIKMCLEEHSYSSSVLHFMAI-----------------ILVGLPI 524
                      |.:..| |.....:||.  ::..|::.:..:                 :|....:
  Rat   496 ----------PLIKYCWLFFTPAVCLA--TFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSM 548

  Fly   525 LAIPAYGFYYIHQRPGSISELFRATDWYPVEMEYRQQYGELVQKSE 570
            :.|||:..|.:....|.:.|..|.. ..|.|        :|.|||:
  Rat   549 VCIPAWSIYKLRTLKGPLRERLRQL-VCPAE--------DLPQKSQ 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	109/515 (21%)
Slc6a13	XP_006237280.2	SLC5-6-like_sbd	32..581	CDD:382020	124/607 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000