Protein Alignment CG13793 and Slc6a4

DIOPT Version :9

• Sequence 1: NP_609136.2
• Gene: CG13793 / 34047
• FlyBaseID: FBgn0031935
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_034614.2
• Gene: Slc6a4 / 15567
• MGIID: 96285
• Length: 630
• Species: Mus musculus
• Alignment Length: 594
• Identity: 145/594 - (24%)
• Similarity: 248/594 - (41%)
• Gaps: 127/594 - (21%)

  Fly    12 RGNWEKPTDYIFACFGLALKLDIFVASFWFF-----FNTGIFGMVPYLMYMVIYLVPIMVIHSYM 71
            |..|.|..|::.:..|.|:.|    .:.|.|     .|.|...::||.:..:...:|:..:...:
Mouse    79 RETWGKKMDFLLSVIGYAVDL----GNIWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELAL 139

  Fly    72 GQFSSSGFISAF-RLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPW-SCEGFK 134
            ||:..:|.||.: ::.|:|||:||....:...:..||....|..|.::::||...||| ||:  .
Mouse   140 GQYHRNGCISIWKKICPIFKGIGYAICIIAFYIASYYNTIIAWALYYLISSFTDQLPWTSCK--N 202

  Fly   135 SWQ---------NDTIAKWSICNATIAEEVAKETENDTYFYITNIHVPSVLYFKSHFESFQNDSE 190
            ||.         .|.|. |::.:.:.|||          ||:            .|.........
Mouse   203 SWNTGNCTNYFAQDNIT-WTLHSTSPAEE----------FYL------------RHVLQIHQSKG 244

  Fly   191 LNDY-EISWHLSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFLPGAHL 254
            |.|. .|||.|:....|::..|.|..:|..:.:  ||.:.........:|.|..||...||||..
Mouse   245 LQDLGTISWQLALCIMLIFTIIYFSIWKGVKTS--GKVVWVTATFPYIVLSVLLVRGATLPGAWR 307

  Fly   255 GLKNYMTPSIEEFVVGTSSTFIMALQAF---GAGWGSVITLSSFNGFKTNIMSYSWIISFGQIFI 316
            |:..|:.|:.:: ::.|......|.|.|   |.|:|.::..:|:|.|..|....:.:.|......
Mouse   308 GVVFYLKPNWQK-LLETGVWVDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMT 371

  Fly   317 YIMFGMVSFMLEHYFLGLPKPLFETQVINHWV-----------LFLSSASALSSLGWPNLWTFIY 370
            ..:.|.|.|.:..|.         .::.|..|           ||::.|.|::::.....:..|:
Mouse   372 SFVSGFVIFTVLGYM---------AEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIF 427

  Fly   371 YTMLLMAALIVITTQIFTILQSLFDEFEQLRAKKQE-------VT--LGLI-----GGLAVCSLY 421
            :.||:...|......:..::.::.|||..:.||::|       :|  ||.:     ||..|.:|.
Mouse   428 FLMLITLGLDSTFAGLEGVITAVLDEFPHIWAKRREWFVLIVVITCILGSLLTLTSGGAYVVTLL 492

  Fly   422 --FCTNHGVLYFAILSIDAIFSQTLLHLLLLLVVLWVYGRDRFQKDIKFMLG-QPFASWKV---- 479
              :.|...||..|:  |:|:            ||.|.||..:|..|:|.||| .|...|::
Mouse   493 EEYATGPAVLTVAL--IEAV------------VVSWFYGITQFCSDVKEMLGFSPGWFWRICWVA 543

  Fly   480 ----FILRFVAPPTLVIC--LVLEIKMCLEEHSYSSSVLHFMAII--LVGL-PILAIPAYGFYYI 535
                |:|       .:||  |:...::.|.:::|.    |:..|:  .:|. .::.||.|..|.:
Mouse   544 ISPLFLL-------FIICSFLMSPPQLRLFQYNYP----HWSIILGYCIGTSSVICIPIYIIYRL 597

  Fly   536 HQRPGSISE 544
            ...||::.|
Mouse   598 ISTPGTLKE 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	130/536 (24%)
Slc6a4	NP_034614.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..63
		5HT_transport_N	24..64	CDD:281488
		SLC6sbd_SERT	79..615	CDD:271399	145/594 (24%)
		Interaction with RAB4A. /evidence=ECO:0000250	616..624

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810