DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13793 and Slc6a9

DIOPT Version :9

Sequence 1:	NP_609136.2	Gene:	CG13793 / 34047	FlyBaseID:	FBgn0031935	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001342104.1	Gene:	Slc6a9 / 14664	MGIID:	95760	Length:	652	Species:	Mus musculus

Alignment Length:	587	Identity:	145/587 - (24%)
Similarity:	268/587 - (45%)	Gaps:	57/587 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DLNRGNWEKPTDYIFACFGLALKL-DIFVASFWFFFNTGIFGMVPYLMYMVIYLVPIMVIHSYMG 72
            :|.||||....:::....|.|:.| :::...:..:.|.|...|.||.:.::...:|:..:....|
Mouse    43 NLTRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFG 107

  Fly    73 QFSSSGFISAFRLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPWS-CEGFKSW 136
            ||:|.|.:..:|:||:|||:||..:.::..:.|||.:...:...:..:|....|||: |.  ..|
Mouse   108 QFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCN--NPW 170

  Fly   137 QN-DTIAKWSICNATIAEEVAKETENDTYF--YITNIHVPSVLYFKSHFESFQNDSELNDYEISW 198
            .. |........|.|.....|..:.|.::.  |......||..|::.:.....:|.. |..|:..
Mouse   171 NTPDCAGVLDASNLTNGSRPAALSGNLSHLFNYTLQRTSPSEEYWRLYVLKLSDDIG-NFGEVRL 234

  Fly   199 HLSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFLPGAHLGLKNYMTPS 263
            .|.|...:.|..:.....:..:.:  ||.:.:.......:|.:.|||.:.|.||..|:..|:||.
Mouse   235 PLLGCLGVSWVVVFLCLIRGVKSS--GKVVYFTATFPYVVLTILFVRGVTLEGAFTGIMYYLTPQ 297

  Fly   264 ----IEEFVVGTSSTFIMALQAFGAGWGSVITLSSFNGFKTNIMSYSWIISFGQIFI-----YIM 319
                :|..|.|.:::.|  ..:.|..||.:||::|:|.|..|....|.|||......     :::
Mouse   298 WDKILEAKVWGDAASQI--FYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVI 360

  Fly   320 FGMVSFMLEHYFLGLPKPLFETQVINH--WVLFLSSASALSSLGWPNLWTFIYYTMLLMAALIVI 382
            |.::.||..|  ||:.    .::|.:|  .:.|::...||:.|....||:.:::.||::..|...
Mouse   361 FSILGFMANH--LGVD----VSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQ 419

  Fly   383 TTQIFTILQSLFDEF--EQLRAKKQEVTLGLIGGLAVCSLYF---CTNHGVLYFAIL--SIDAIF 440
            ...:.|::.::.||.  |.:..||..|||    |:||.....   .|:...:|:.:|  :..|.|
Mouse   420 FCLLETLVTAIVDEVGNEWILQKKTYVTL----GVAVAGFLLGIPLTSQAGIYWLLLMDNYAASF 480

  Fly   441 SQTLLHLLLLLVVLWVYGRDRFQKDIKFMLGQPFASWKVFILRFVAPPT---LVICLVLEIKMCL 502
            |..::..::.:.::::||...:.:||:.|||.|...:.....|||:|..   ::|..|::.:...
Mouse   481 SLVVISCIMCVSIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILIFTVIQYRPIT 545

  Fly   503 EEH----SYSSSVLHFMAIILVGLPILAIPAYGFYYIHQRPGS--ISELFRAT----DWYPVEME 557
            ..|    .::.::...||:    ..::.||.|..:.:.:..|.  :..|..||    ||.|..:|
Mouse   546 YNHYQYPGWAVAIGFLMAL----SSVICIPLYALFQLCRTDGDTLLQRLKNATKPSRDWGPALLE 606

  Fly   558 YR 559
            :|
Mouse   607 HR 608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	125/504 (25%)
Slc6a9	NP_001342104.1	SLC6sbd_GlyT1	30..613	CDD:212067	145/587 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810