Protein Alignment CG13793 and Slc6a5

DIOPT Version :10

• Sequence 1: NP_609136.2
• Gene: CG13793 / 34047
• FlyBaseID: FBgn0031935
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_006540608.1
• Gene: Slc6a5 / 104245
• MGIID: 105090
• Length: 831
• Species: Mus musculus
• Alignment Length: 610
• Identity: 153/610 - (25%)
• Similarity: 264/610 - (43%)
• Gaps: 81/610 - (13%)

  Fly    12 RGNWEKPTDYIFACFGLALKL-DIFVASFWFFFNTGIFGMVPYLMYMVIYLVPIMVIHSYMGQFS 75
            ||||....|:|.:..|.|:.| :::...:..|.|.|...::||||.:.:..:||..:...:|||:
Mouse   225 RGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFA 289

  Fly    76 SSGFISAFRLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPW-SCEGFKSWQND 139
            |.|.:|.::..|..:|.|...|.:::.:.|||.:.....|.::..||...||| ||.  ..|...
Mouse   290 SQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCN--NPWNTP 352

  Fly   140 TI---AKWSICNATIAEEVAKETENDTYFYITNIHVPSVLYFKSHFESFQNDSELNDY------- 194
            ..   .|..:.:..|.:....:.:|.|:......::..|.:.....::|.:.||  :|
Mouse   353 ECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQTNKTFVSGSE--EYFKYFVLK 415

  Fly   195 ---------EISWHLSGLFALVWATIAFIFYKFSEPAK----FGKCIRYMVIGTVALLLVCFVRF 246
                     ||.|.|:....|.|..:      ::..||    .||.:.:.......:|::..:|.
Mouse   416 ISAGIEYPGEIRWPLAFCLFLAWVIV------YASLAKGIKSSGKVVYFTATFPYVVLVILLIRG 474

  Fly   247 LFLPGAHLGLKNYMTPSIEEFVVGT----SSTFIMALQAFGAGWGSVITLSSFNGFKTNIMSYSW 307
            :.||||..|:..::||..|:....|    ::|.|..  :..|.||.:|||||:|.|..|....:.
Mouse   475 VTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFF--SLSAAWGGLITLSSYNKFHNNCYRDTL 537

  Fly   308 II----SFGQIFI-YIMFGMVSFMLEHYFLGLPKPLFETQVINHWVLFLSSASALSSLGWPNLWT 367
            |:    |...||. :::|.::.||.....:.:.....:    ...:.|:....||:.|.....|.
Mouse   538 IVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQ----GPGIAFVVYPEALTRLPLSPFWA 598

  Fly   368 FIYYTMLLMAALIVITTQIFTILQSLFDEF-EQLRAKKQEVTLGLIGGLAVCSLYF------CTN 425
            .|::.|||...|..:...|.||:.|:.||| :.||..|...|||      .|..:|      .|.
Mouse   599 IIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLG------CCICFFIMGFPMITQ 657

  Fly   426 HGVLYFAIL-SIDAIFSQTLLHLLLLLVVLWVYGRDRFQKDIKFMLG-QPFASWKVFILRFVAPP 488
            .|:..|.:: :..|.::..::.:..|:.:.:|||..||.:||:.|:| :|...||| ...||.|.
Mouse   658 GGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFKPNIFWKV-CWAFVTPT 721

  Fly   489 TLVICLVLEI----KMCLEEHSYS--SSVLHFMAIILVGLPILAIPAYGFYYIHQRPGSISELFR 547
            .|...|....    .|....:.|.  |.||.:   :::...::.||......::..||...|..:
Mouse   722 ILTFILCFSFYQWEPMTYGSYRYPNWSMVLGW---LMLACSVIWIPIMFVIKMYLAPGRFIERLK 783

  Fly   548 AT-----DWYPVEMEYR-QQYGELV 566
            ..     ||.|...::| ::|..::
Mouse   784 LVCSPQPDWGPFLAQHRGERYKNMI 808

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	134/521 (26%)
Slc6a5	XP_006540608.1	SLC6sbd_GlyT2	225..821	CDD:271389	153/610 (25%)