Protein Alignment CG13793 and slc6a8

DIOPT Version :10

• Sequence 1: NP_609136.2
• Gene: CG13793 / 34047
• FlyBaseID: FBgn0031935
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_002935539.1
• Gene: slc6a8 / 100489909
• XenbaseID: XB-GENE-986840
• Length: 644
• Species: Xenopus tropicalis
• Alignment Length: 613
• Identity: 145/613 - (23%)
• Similarity: 254/613 - (41%)
• Gaps: 103/613 - (16%)

  Fly     6 FSPDLNRG-----NWEKPTDYIFACFGLALKL-DIFVASFWFFFNTGIFGMVPYLMYMVIYLVPI 64
            |.|:...|     .|....|:|.:|.|.|:.| :::...:..:.|.|...::||::..::..:||
 Frog    47 FPPNCKEGIPERDTWTSQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYILIAILGGIPI 111

  Fly    65 MVIHSYMGQFSSSGFISAFRLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPWS 129
            ..:...:|||..:|.|:.:.::|||:|:|:.|:.:......||.:.....:.:::.||...||||
 Frog   112 FFLEIALGQFMKAGSIAVWNIAPLFQGIGFASVVIVFFCNTYYILILTWGVYYLVKSFSAVLPWS 176

  Fly   130 -CEGFKSWQN----DTIAKWSICNATIAEEVAKETEN---DTYFYITNIHVPSVLYFKSHFESFQ 186
             |.  .:|.:    |...:....|.|........|.|   |....||......||...|..:...
 Frog   177 HCN--NTWNSPDCVDIFRQEDCTNGTANSTFGNLTCNELADKVSPITEFWEKKVLRLSSGLDDIG 239

  Fly   187 NDSELNDYEISWHLSGLFALV--WATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFL 249
            :        |:|.|  |..|:  |..:.|..:|..:..  ||.:.:.......:||:..||...|
 Frog   240 S--------INWEL--LLCLIGCWLLVYFCVWKGVKST--GKIVYFTATFPYVVLLILLVRGAML 292

  Fly   250 PGAHLGLKNYMTPSIEEFVVGTSSTFIMA----LQAFGAGWGSVITLSSFNGFKTNIMSYSWI-- 308
            |||..|:..|:.|...:  :||:..:|.|    ..::..|.|::..|.|:|.|..:....::|
 Frog   293 PGATEGIIYYLKPDWSK--LGTAQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNDCYKDAFILA 355

  Fly   309 -ISFGQIFI--YIMFGMVSFMLEHYFLGLPKPLFETQVINHWVLFLSSASALSSLGWPNLWTFIY 370
             |:.|..|.  :::|.::.||.....:.:.| :.|:   ...:.|::...|:|.:....||:.::
 Frog   356 VINSGTSFFAGFVVFSILGFMANEQGVDISK-VAES---GPGLAFIAYPRAVSLMPVAPLWSALF 416

  Fly   371 YTMLLMAAL---IVITTQIFTILQSLFDEFEQLRAKKQEVTLGLIGGLAVCSLYF------CTNH 426
            :.|||:..|   .|....:.|.:..|.......|.:: |:.:.:     .|::.|      .|..
 Frog   417 FFMLLLLGLDSQFVGVEGLITAILDLLPARYYFRFQR-EIAVAI-----CCAIMFLIDLSMLTEG 475

  Fly   427 GVLYFAILSIDAIFSQTLLHLLL--LLVVLWVYGRDRFQKDIKFMLG-QPFASWKVFILRFVAPP 488
            |:..|.:....:....|||....  .:||.||||.|||..||..|:| :|| .|..:...||.|
 Frog   476 GMYVFQLFDYYSASGMTLLWQTFWQCVVVAWVYGADRFMDDIARMIGYRPF-PWMKWCWSFVTP- 538

  Fly   489 TLVICL------VLEIKMCLEEHSYS--------------SSVLHFMAIILVGLPILAIPAYGFY 533
              .:|:      ::..|.....:||:              ||             :|.:|....|
 Frog   539 --FVCMAIFLFNLINYKPLTYNNSYTYPWWGEAIGWGFALSS-------------MLCVPVTFLY 588

  Fly   534 YIHQRPGSISELFRATD---WYPVEMEY 558
            .|....||:.|.::...   |....:||
 Frog   589 KITCAKGSLRERWQHLTKPIWGAHHLEY 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	126/516 (24%)
slc6a8	XP_002935539.1	SLC5-6-like_sbd	58..644	CDD:444915	142/602 (24%)