Protein Alignment Ntl and slc6a17

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001243653.1
• Gene: slc6a17 / 798635
• ZFINID: ZDB-GENE-030131-8187
• Length: 730
• Species: Danio rerio
• Alignment Length: 588
• Identity: 191/588 - (32%)
• Similarity: 309/588 - (52%)
• Gaps: 87/588 - (14%)

  Fly    21 DENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIPLFYMEILIG 85
            ::.|..|.||.::||:.:|:::|:||||||||||.::||.|:|:||.:::||.|||||::|:.:|
Zfish    60 EDGRPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLVPYFILLILIGIPLFFLELAVG 124

  Fly    86 QFSSTGCTGMFR-MTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFFKKVPWEDCSNSWN 149
            |....|..|::. :.|.|.|.|.:.::|..:...||:|||.:.|...|..|...:||.||....|
Zfish   125 QRIRRGSIGVWNYVCPRLGGIGASSLMVCGFVGLYYNVIIGWSIFYFFQSFQYPLPWSDCPIRKN 189

  Fly   150 TDDCVTASDMGKQNSSDVFKTSADEFFHLEVLRISTDISDLGGMVWEQLTALIITWIIIYFCLMR 214
            ....:...:..|.:::..       |::.|.|.|::.|:|.||:.|....:|:..|||:...:::
Zfish   190 GSQAIVEPECEKSSATTY-------FWYRETLNITSTIADSGGLNWRMTLSLLAAWIIVCLAVIK 247

  Fly   215 GIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDLKVWADAAVQMFFGI 279
            ||:|.|||:||:..|||::||..|:||..|.||..||.....|:...:|:.:||.:||.|:||.:
Zfish   248 GIQSSGKVMYFSSLFPYVVLFCFLVRGLFLKGAVDGIAHMFTPKLEIMLEPQVWREAATQVFFAL 312

  Fly   280 GPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGF----LSEKSGIP-VESV 339
            |.|:||::..:|::...||...|:||:..||..||:||..|||:||||    ::||..:. .|.:
Zfish   313 GLGFGGVIAFSSYNKRDNNCHFDAVLVSVINFLTSILATLVVFAVLGFKANIMNEKCVVENAEKI 377

  Fly   340 -----------------------------------------------------------ATGGAG 345
                                                                       |..|.|
Zfish   378 LGYLNSNVLSHDLIPPHVNFSHLTTSDYAEMYGVIKIVKEDSFAQLGLEQCLLEDELNKAVQGTG 442

  Fly   346 LAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILDEWYWVRSHKCKLTLISC 410
            |||:.:.||:...|....|::||||||..||:.|:...:..|.:.|||.:   :..|..||:..|
Zfish   443 LAFIAFTEAMTHFPASPFWSVMFFFMLINLGLGSMIGTMTGITTPILDTF---KIRKEYLTVGCC 504

  Fly   411 LIFLGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEIIMVAWIYGIKNFMLDVEFMLGKRPTL 475
            ::......:.....|.:.:.:||.||:.:.:.::.::|.:.||||||.|.||.|:|.|||.||..
Zfish   505 IVAFLCGLLFVQRSGNYFVTMFDDYSAGLPLTIVVILENVSVAWIYGTKRFMQDLEDMLGFRPYS 569

  Fly   476 YWRIVWQVVTPVIIIFILITSIV--FIRTITYNN----------IPYPQWAIIIGWASCFTSVMW 528
            .:..:|:.|:||.:|.::..|:|  .|..:.||.          ..||.|||::.:|....:::.
Zfish   570 VYFYLWKYVSPVCLIILISASVVEMAISPLGYNAWVQDLAMERFQSYPPWAIVMCFALIIVAMLP 634

  Fly   529 IPL 531
            :||
Zfish   635 LPL 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	191/585 (33%)
slc6a17	NP_001243653.1	SLC5-6-like_sbd	63..651	CDD:444915	191/585 (33%)