Protein Alignment Ntl and zgc:158427

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001073546.2
• Gene: zgc:158427 / 790932
• ZFINID: ZDB-GENE-061215-110
• Length: 579
• Species: Danio rerio
• Alignment Length: 577
• Identity: 225/577 - (38%)
• Similarity: 348/577 - (60%)
• Gaps: 22/577 - (3%)

  Fly    19 ERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIPLFYMEIL 83
            |:.|.||.|..|:||:|::.|..:|:||||||||||||:||..||||||:.|:..|:|||.:|..
Zfish     6 EKIEERGFWGKKTEFLLAVAGNVVGLGNVWRFPYLCYRNGGGVFLIPYLVFVVTCGVPLFLLETA 70

  Fly    84 IGQFS-STGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFFKKVPWEDCSNS 147
            :|||: ..|.|...|:.||.:|.|.|..:...|...|:::|:::.:..:...|..::||..|.|.
Zfish    71 MGQFTHEGGITCWHRLCPLAQGIGYAGQLTVLYSCMYFTIILAWALFYLISSFSSQLPWASCDNI 135

  Fly   148 WNTDDCV--TASDMGKQNSSDVF---KTSADEFFHLEVLRISTDISDLGGMVWEQLTALIITWII 207
            ||||:||  .|.::....::.:.   .::|.||:...||.:|..|.|:|.:.||.|..||..|||
Zfish   136 WNTDNCVNLAAGNLTFNRTTQMLINSTSAATEFWERRVLSLSGGIEDIGKINWEILLCLIAMWII 200

  Fly   208 IYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDLKVWADAA 272
            .|||:.:|:||.|||||||..|||::|.:|||||.|||||.:||.||||||..||.|.:||.:|.
Zfish   201 CYFCIWKGVKSTGKVVYFTATFPYVMLIVLLIRGLTLPGALQGIVFYLYPEPARLADPQVWMEAG 265

  Fly   273 VQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGFLSEKSGIPVE 337
            .|:||......|.::::.|::.:.||...|...:..:|..||.:|||.|||||||::...|:|:|
Zfish   266 TQIFFSYSVIGGVLISLGSYNQYNNNCYRDCFWLCLLNSGTSFVAGFAVFSVLGFMAHVQGVPIE 330

  Fly   338 SVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILDEWYWV---R 399
            .||..|.||||:.||:|:|::|.|||||:.||.|:.|||:|:.||.:|.:::|::|.:..|   .
Zfish   331 EVAESGPGLAFIAYPQAVAMMPFPQLWAVCFFIMIILLGLDTQFVSVECVITSVMDLFPEVLRRA 395

  Fly   400 SHKCKLTLISCL-IFLGLSSIMCTNGGMFILQLFDWYS-SAIAVIVICLVEIIMVAWIYGIKNFM 462
            ..:..|.|:.|| .|.| ..||.|.|||::.||||.|: :...::.:.:.|.:.:.||:|.:...
Zfish   396 GRRELLVLLLCLTCFFG-QLIMVTEGGMYVFQLFDNYACNGACLLFLSVFESLAIGWIFGAEKMF 459

  Fly   463 LDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTITYNN-IPYPQWAIIIGWASCFTSV 526
            ..:|.|...||..::.:.|:.:||::.:...:.|:|....:|:|. ..||.||.::||....:|:
Zfish   460 DIIEDMTESRPNYWFMLCWKYLTPLVSLTSFVYSMVRYTPLTFNRWYIYPDWAYVLGWLLALSSI 524

  Fly   527 MWIPLYIFYIMIRKRATLCDSLKKRLKPLDWTPADPQDRAEYEAFRRQRRMPGFMSD 583
            :.:|.:....|...:.    |||:|.:.|    :.|:..... :|::.::....|.|
Zfish   525 LLVPAWALGQMCAGKG----SLKQRWRHL----SSPETNFPL-SFKQVQKQTAEMED 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	218/541 (40%)
zgc:158427	NP_001073546.2	SLC6sbd-TauT-like	11..552	CDD:271387	219/549 (40%)