Protein Alignment Ntl and slc6a13

DIOPT Version :9

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001072913.1
• Gene: slc6a13 / 780375
• XenbaseID: XB-GENE-5947897
• Length: 601
• Species: Xenopus tropicalis
• Alignment Length: 579
• Identity: 237/579 - (40%)
• Similarity: 356/579 - (61%)
• Gaps: 24/579 - (4%)

  Fly     6 PPTTNATRKDKRIERDE---NRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYL 67
            |||.....|:.::|..:   .||||.:|.||:||:.|..||:|||||||||||::||.||.||||
 Frog    16 PPTKPLMEKEPKMEDGDMMIERGQWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYL 80

  Fly    68 LMVILAGIPLFYMEILIGQFSST-GCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMI 131
            :.:...|||:|::|..:||::|. |.|...::.||.:|.|.:..|:.....|||.|::::.:..:
 Frog    81 IFLFTCGIPVFFLETALGQYTSQGGVTAWRKICPLFEGIGYSSQVIVMLLNCYYIVVLAWALFYL 145

  Fly   132 FYCFFKKVPWEDCSNSWNTDDCVTASDMGKQNSSDVF----KTSADEFFHLEVLRISTDISDLGG 192
            |..|..::||..|.:||||::|:   |..|.||:...    .:|..||:...|||||..|.::||
 Frog   146 FNSFTSELPWASCGHSWNTENCL---DFYKGNSTHNVTLNGTSSVIEFWERRVLRISDGIDNIGG 207

  Fly   193 MVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYP 257
            :.||....|::.|||.|||:.:|:||.|||||||..||||:|.:|||||.:||||..||:|||||
 Frog   208 LHWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLIVLLIRGVSLPGALTGIQFYLYP 272

  Fly   258 EWHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVF 322
            :..||.|.:||.||..|:||......|.:..:.|::.:.||...|.|.:..:|..||.:|||.:|
 Frog   273 DLSRLQDPQVWMDAGTQIFFSYAICLGCLTALGSYNKYNNNCYRDCVALCFLNSGTSFVAGFAIF 337

  Fly   323 SVLGFLSEKSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAI 387
            |:|||::|:.|:.:..||..|.||||:.||.|::::|...|||..||||:.|||:||.||.:|::
 Frog   338 SILGFMAEEQGVHISDVAESGPGLAFIAYPRAVSMMPFSPLWACFFFFMVILLGLDSQFVCVESL 402

  Fly   388 MSSILDEWYWVRSHKCKLTL----ISCLIFL-GLSSIMCTNGGMFILQLFDWY-SSAIAVIVICL 446
            :::::|.:..:...|.:..|    :|.:.|| ||  ||.|.|||::.||||:| :|.:.::.:.:
 Frog   403 VTAVVDMYPTIFRKKNRRELLILGVSMISFLVGL--IMLTEGGMYVFQLFDYYAASGMCLLFVAI 465

  Fly   447 VEIIMVAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTITYN-NIPY 510
            .|.:.|.|:||..||...||.|:|.|||...:..|..|||.:.:...:.|:|....:||| :..|
 Frog   466 FETLCVGWVYGADNFYDKVEHMIGYRPTGIIKYCWLFVTPAVCMATFLFSLVKYTPLTYNKHYVY 530

  Fly   511 PQWAIIIGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPLDWTPADPQDRAEYE 569
            |.|...|||....:|::.|||::.|    |.:|:..||.:|.:.|.:...|...:.:.|
 Frog   531 PWWGDAIGWLLALSSMVCIPLWVGY----KLSTIKGSLMERFRQLTFPDPDLPQKTQCE 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:294310	229/541 (42%)
slc6a13	NP_001072913.1	SLC5-6-like_sbd	37..579	CDD:382020	231/550 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010