Protein Alignment Ntl and Slc6a17

DIOPT Version :9

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001028251.1
• Gene: Slc6a17 / 613226
• RGDID: 1587185
• Length: 727
• Species: Rattus norvegicus
• Alignment Length: 676
• Identity: 205/676 - (30%)
• Similarity: 333/676 - (49%)
• Gaps: 108/676 - (15%)

  Fly     9 TNATRKDKRIERD-ENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVIL 72
            |...:|....|.| |:|..|.||.::||:.:|:::|:||:|||||||.::||.|:|:|||:::|:
  Rat    44 TGGKQKVAEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLII 108

  Fly    73 AGIPLFYMEILIGQFSSTGCTGMFR-MTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFF 136
            .|||||::|:.:||....|..|::. :.|.|.|.|.:..:|..:...||:|||.:.:...|..|.
  Rat   109 IGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSVFYFFKSFQ 173

  Fly   137 KKVPWEDCSNSWNTDDCVTASDMGKQNSSDVFKTSADEFFHLEVLRISTDISDLGGMVWEQLTAL 201
            ..:||.:|....|....|...:..|.:::..       |::.|.|.||..||:.||:.|:....|
  Rat   174 YPLPWSECPVIRNGTVAVVEPECEKSSATTY-------FWYREALDISNSISESGGLNWKMTVCL 231

  Fly   202 IITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDLK 266
            ::.|.|:...:::||:|.|||:||:..|||::|...|:||..|.||..||.....|:..::||.:
  Rat   232 LVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQ 296

  Fly   267 VWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGF---- 327
            ||.:||.|:||.:|.|:||::..:|::...||...|:.|:..||.|||:||..|||:||||
  Rat   297 VWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANI 361

  Fly   328 LSEKSGIP-VESV--------------------------------------------ATG----- 342
            ::||..:. .|.:                                            |.|
  Rat   362 MNEKCVVENAEKILGYLNSNVLSRDLIPPHVNFSHLTTKDYSEMYNVIMTVKEKQFSALGLDPCL 426

  Fly   343 ----------GAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILDEWYW 397
                      |.||||:.:.||:...|....|::|||.||..||:.|:...:..|.:.|:|.:
  Rat   427 LEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTF-- 489

  Fly   398 VRSHKCKLTLISCL--IFLGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEIIMVAWIYGIKN 460
             :..|...|:..|:  .|:||  :.....|.:.:.:||.||:.:.:.||.::|.|.||||||.|.
  Rat   490 -KVPKEMFTVGCCVFAFFVGL--LFVQRSGNYFVTMFDDYSATLPLTVIVILENIAVAWIYGTKK 551

  Fly   461 FMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFI------------RTITYNNIPYPQW 513
            ||.::..|||.||..::..:|:.|:|:.:..:...||:.:            .......:.:|.|
  Rat   552 FMQELTEMLGFRPYRFYFYMWKFVSPLCMAVLTTASIIQLGVSPPGYSAWIKEEAAERYLYFPNW 616

  Fly   514 AI-----IIGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPLDWTPADPQDRAEYEAFRR 573
            |:     :|..|:....|::| |..|:::.....||..|.||.....|.:..:..|...:...:.
  Rat   617 AMALLITLIAVATLPIPVVFI-LRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKV 680

  Fly   574 QRRMPGFM----------SDTDMESS 589
            ....|..|          |.:.:|||
  Rat   681 PSEAPSPMPTHRSYLGPGSTSPLESS 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:294310	192/613 (31%)
Slc6a17	NP_001028251.1	SLC6sbd_NTT4	60..648	CDD:271403	187/600 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	680..727		6/27 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910